| Gene info: |
Fas gene mutations have been suggested to have a role in testicular germ cell tumors, Functional impairment of the Fas / Fas Ligand system is associated with the development and progression of malignancies, Ligation of Fas by Fas Ligand or an anti Fas cross linking antibody, The apoptosis of lymphocytes, Tumor cells frequently exhibit de novo expression of Fas Ligand, and immune escape of the tumor cells, is usually induced by the Fas/Fas Ligand system, metastatic spread, triggers activation of the caspase cascade, which occurs in autoimmune diseases, which plays a significant role in local tissue destruction, Fas Ligand is an important member of the tumour necrosis factor (TNF) superfamily involved in membrane mediated apoptosis |
| Gene names: |
ALPS1B, APT1LG1, APTL, Apoptosis antigen ligand, CD178, CD95-L, CD95L, FASL, TNFSF6, Tumor necrosis factor ligand superfamily member 6, APTL |
| Antibodie's label: |
Biotin |
| Purity: |
Anti-hFasL/Apo1 specific antibody was purified by affinity chromatography and then biotinylated |
| Ab raised in: |
Goat |
| Type: |
Polyclonal |
| Antigen: |
98%) recombinant hFasL/Apo1 (human FasL/Apo1), Produced from sera of goats pre-immunized with highly pure (> |
| Immuno application: |
Western Blot, ELISA |
| Antibody advice: |
Sandwich: To detect hFasL/Apo1L by sandwich ELISA (using 100 &, This biotinylated polyclonal antibody, Used in conjunction with compatible secondary reagents, Used in conjunction with compatible secondary reagents the detection limit for recombinant hFasL/Apo1 is 1, Western Blot: To detect hFasL/Apo1 by Western Blot analysis this antibody can be used at a concentration of 0, allows the detection of at least 0, allows the detection of at least 0, in conjunction with our Polyclonal Anti-Human FasL/Apo1L (XP-5130) as a capture antibody, under either reducing or non-reducing conditions, #956, #956, 0 ng/lane, 0 ug/mL of this antibody is required, 1 - 0, 15-0, 2 - 0, 2 ng/well of recombinant hFasL/Apo1, 2 ug/mL, 25 - 1, 30 ug/mL, 4 ng/well of recombinant hFasL/Apo1L, 5 - 3, ELISA: To detect hFasL/Apo1 by direct ELISA (using 100 &, L/well antibody solution) a concentration of 0, L/well antibody solution) this antibody can be used at a concentration of 0 |
| Keep at: |
Avoid repeated freeze-thaw cycles, Frozen aliquots are stable for at least 6 months when stored at -20 grades C, The reconstituted antibody is stable for at least two weeks at 2-8 grades C, Fas Ligand antibody is stable for at least 2 years from date of receipt at -20 grades C |
| Works with: |
Human |
| Omim nr: |
1345957 |
| Ncbi nr: |
P48023 |
| Vial with antibody: |
Lyophilized |
| NCBI GENE nr: |
356 |
| GENE symbol: |
FASLG |
| Antigene name: |
member 6), Fas ligand (TNF superfamily |
| Source: |
Homo sapiens |
| Protein nr: |
P48023 |
| Description: |
FAS ligand and other ligands are binding to the receptor for signaling pathways for example in apoptosis or JNK signaling, Freeze thaw will destroy a percentage in every cycle and should be avoided, Receptor agonists are often tested for drug development, C in a fridge short term in a concentrated dilution, This antibody needs to be stored at + 4° |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by proscience they should be stored frozen at - 24° |
| Gene target: |
Fas Ligand |
| Short name: |
anti-Fas Ligand Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody to, Antibody |
| Alternative name: |
member 6) Ligand (Antibody to), antibody to-Fas (TNF receptor superfamily |
| Alternative technique: |
antibodies |