| Gene info: |
Adiponectin function appears to be regulated by phosphatidylinositol 3 kinase (PI3K) since Adiponectin secretion is blocked by pharmacologic inhibitors of this kinase, Adiponectin improves the ability of insulin to suppress glucose production, Adiponectin is a circulating protein that is secreted exclusively by differentiated adipocytes, Adiponectin is implicated as a regulator of whole body energy homeostasis, Adiponectin mRNA is induced >, Adiponectin mRNA is significantly reduced in adipose tissue of obese patients with Type 2 diabetes, During adipocyte differentiation, Leptin, The structural similarity of Adiponectin to TNF alpha suggests that Adiponectin may play a role in pathogenesis of insulin resistance in Type 2 diabetes, also known as Acrp30 or Adiponectin, and Adipocyte Complement Related protein of 30 kDa, at sub physiological levels, such as Lipoprotein Lipase, thereby linking adipose tissue to whole body glucose regulation, 100 fold, Adipose cells produce and secrete numerous physiologically important proteins |
| Gene names: |
30 kDa adipocyte complement-related protein, ACDC, ACRP30, ADIPQTL1, ADPN, APM-1, APM1, Adiponectin, GBP28, ACDC |
| Antibodie's label: |
Biotin |
| Ab raised in: |
Goat |
| Type: |
Polyclonal |
| Antigen: |
98%) recombinant (human Adipolean), Produced from sera of goats pre-immunized with highly pure (> |
| Immuno application: |
Western Blot, ELISA |
| Antibody advice: |
Used in conjunction with compatible secondary reagents, Used in conjunction with compatible secondary reagents the detection limit for recombinant hAdipolean is 1, Western Blot: To detect hAdipolean by Western Blot analysis this antibody can be used at a concentration of 0, allows the detection of at least 0, under either reducing or non-reducing conditions, #956, 0 ng/lane, 1 - 0, 15 - 0, 2 ng/well of recombinant hAdipolean, 2 ug/mL, 30 ug/mL, 5 - 3, ELISA: To detect hAdipolean by direct ELISA (using 100 &, L/well antibody solution) this antibody can be used at a concentration of 0 |
| Keep at: |
Avoid repeated freeze-thaw cycles, Frozen aliquots are stable for at least 6 months when stored at -20 grades C, The reconstituted antibody is stable for at least two weeks at 2-8 grades C, Adipolean antibody is stable for at least 2 years from date of receipt at -20 grades C |
| Works with: |
Human |
| Omim nr: |
2493789 |
| Ncbi nr: |
Q15848 |
| Vial with antibody: |
Lyophilized |
| NCBI GENE nr: |
9370 |
| GENE symbol: |
ADIPOQ |
| Antigene name: |
C1Q and collagen domain containing, adiponectin |
| Source: |
Homo sapiens |
| Protein nr: |
Q15848 |
| Description: |
Freeze thaw will destroy a percentage in every cycle and should be avoided, C in a fridge short term in a concentrated dilution, This antibody needs to be stored at + 4° |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by proscience they should be stored frozen at - 24° |
| Gene target: |
Adipolean |
| Short name: |
anti-Adipolean Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody to, Antibody |
| Alternative name: |
antibody to-Adipolean (Antibody to) |
| Alternative technique: |
antibodies |