| Category: |
Antibody |
| Concentration: |
BSA free, sodium azide free, 1 mg/ml in 1X PBS |
| Form: |
Purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
PDCD1 / PD-1 |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
, Due to limited knowledge and inability to test the antibody against all known species, Other species not tested, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
FACS, IF, IHC-P |
| Recommended dilutions: |
1ml, 5-1ug/10e6 cells in 0, FACS: 0, Immunofluorescence: 1-2ug/ml, Immunohistochemistry (FFPE): 1-2ug/ml for 30 min at RT |
| Notes: |
Titering of the PD1 antibody may be required for optimal performance |
| Intented use: |
This PD1 antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
Q15116 |
| Purity: |
Purified by protein A Affinity Chromatography |
| Description: |
Anti-PDCD1 is a marker of angioimmunoblastic lymphoma and suggests a unique cell of origin for this neoplasm, B-cells, It is expressed on activated T-cells, PDCD1 is expressed by few B-cells, Unlike CD10 and BCL6, also called PD1 and CD279, and myeloid cells, is a type I transmembrane receptor and a member of the immunoglobin gene superfamily, so may be a more specific and useful diagnostic marker in angioimmunoblastic lymphoma, PDCD1 (Programmed cell death-1 protein) |
| Immunogen: |
A full-length human protein was used as the immunogen for the PD1 antibody |
| Storage: |
Store the PD1 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide) |
| Localization: |
cytoplasmic, Cell surface & |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
PDCD1 / PD-1 |
| Short name: |
PDCD1 / PD-1 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
programmed cellular death 1 / PD-1 (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
CD279 and hPD-1 and hPD-l and hSLE1 and PD-1 and PD1 and SLEB2, Cell surfaces, PDCD1 and IDBG-642702 and ENSBTAG00000011543 and 613842, PDCD1 and IDBG-85346 and ENSG00000188389 and 5133, Pdcd1 and IDBG-184148 and ENSMUSG00000026285 and 18566, protein binding, this GO :0004871 and signal transducer activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005886 and plasma membrane and cellular component this GO :0006915 and apoptotic process and biological process this GO :0006959 and humoral immune response and biological process this GO :0007165 and signal transduction and biological process this GO :0007275 and multicellular organismal development and biological process this GO :0009897 and external side of plasma membrane and cellular component this GO :0016021 and integral component of membrane and cellular component this GO :0031295 and T cell costimulation and biological process this GO :0045087 and innate immune response and biological process, this GO :0004871 : signal transducer activity, this GO :0004871 : signal transducer activity and also this GO :0005515 : protein binding, this GO :0005515 : protein binding, programmed cell death 1 |
| Identity: |
8760 |
| Gene: |
PDCD1 |
More about : PDCD1 |
| Long gene name: |
programmed cell death 1 |
| Synonyms gene: |
SLEB2 |
| Synonyms gene name: |
systemic lupus erythematosus susceptibility 2 |
| Synonyms: |
CD279 PD1 hSLE1 PD-1 |
| Locus: |
2q37, 3 |
| Discovery year: |
1994-05-24 |
| GenBank acession: |
AY206416 |
| Entrez gene record: |
5133 |
| Pubmed identfication: |
7851902 12402038 |
| RefSeq identity: |
NM_005018 |
| Classification: |
CD molecules V-set domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000151342 |