| ELISA kit stock availability: |
Available In Stock |
| ELISA's description: |
>, dual Inhibitor of Her2/EGFR Tyr kinase (IC50=17 nM, mol wt 547, 98%), Tak-285 |
| Category: |
Custom Service |
| S type: |
n/a |
| Antibody's host is: |
see techfile |
| Purification: |
Affinity purified |
| Test: |
Mainly in phosphorylation by specific phosphatases, pH or protein, The duality of this product lies in it's dual specificity to the gene |
| Description: |
Not all receptor antagonist that bind to enzymes are inhibitors, Since blocking an enzyme's activity can kill a pathogen , activator, caspase, esterase inhibitors , lipoprotein, many drugs are enzyme inhibitors, papain, pathway, peptidase, protease , proteinase, trypsin, while enzyme substrates bind and are converted to products in the normal catalytic cycle of the enzyme, , Tissue, acrosin, activity, and decreases its , are , bind to enzymes and increase their , enzymatic activity, enzyme activator ligands or agonists , enzyme receptor , imbalance, metabolic , or correct a , or receptor ligands or receptor antagonists that bind to an , proteins |
| Gene target: |
>, Inhibitor of Her2/EGFR Tyr kinase (IC50=17 nM, mol wt 547, 98%, Tak-285 |
| Short name: |
>, Inhibitor of Her2/EGFR Tyr kinase (IC50=17 nM, mol wt 547, 98%), Tak-285 |
| Label: |
dual |
| Alternative name: |
>, dual suppressor on Her2/epidermal growth factor receptor L-tyrosine phosphorylation catalyst (IC50=17 nanometer, mol wt 547, 98%), Tak-285 |
| Alternative to gene target: |
EGFR and IDBG-16933 and ENSG00000146648 and 1956, EGFR and IDBG-644035 and ENSBTAG00000011628 and 407217, ERBB and ERBB1 and HER1 and mENA and PIG61, Egfr and IDBG-151194 and ENSMUSG00000020122 and 13649, glutamatergic and biological process this GO :0060571 and morphogenesis of an epithelial fold and biological process this GO :0070141 and response to UV-A and biological process this GO :0070374 and positive regulation of ERK1 and ERK2 cascade and biological process this GO :0070435 and Shc-EGFR complex and cellular component this GO :0071230 and cellular response to amino acid stimulus and biological process this GO :0071260 and cellular response to mechanical stimulus and biological process this GO :0071363 and cellular response to growth factor stimulus and biological process this GO :0071364 and cellular response to epidermal growth factor stimulus and biological process this GO :0071392 and cellular response to estradiol stimulus and biological process this GO :0071549 and cellular response to dexamethasone stimulus and biological process, nuclei, this GO :0000139 and this GO lgi membrane and cellular component this GO :0000165 and MAPK cascade and biological process this GO :0000186 and activation of MAPKK activity and biological process this GO :0000902 and cell morphogenesis and biological process this GO :0001503 and ossification and biological process this GO :0001889 and liver development and biological process this GO :0001892 and embryonic placenta development and biological process this GO :0001934 and positive regulation of protein phosphorylation and biological process this GO :0001942 and hair follicle development and biological process this GO :0001948 and glycoprotein binding and molecular function this GO :0003682 and chromatin binding and molecular function this GO :0003690 and double-stranded DNA binding and molecular function this GO :0004672 and protein kinase activity and molecular function this GO :0004709 and MAP kinase kinase kinase activity and molecular function this GO :0004713 and protein tyrosine kinase activity and molecular function this GO :0004714 and transmembrane receptor protein tyrosine kinase activity and molecular function this GO :0004716 and receptor signaling protein tyrosine kinase activity and molecular function this GO :0004871 and signal transducer activity and molecular function this GO :0004888 and transmembrane signaling receptor activity and molecular function this GO :0005006 and epidermal growth factor-activated receptor activity and molecular function this GO :0005102 and receptor binding and molecular function this GO :0005178 and integrin binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005524 and ATP binding and molecular function this GO :0005615 and extracellular space and cellular component this GO :0005622 and intracellular and cellular component this GO :0005634 and nucleus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005768 and endosome and cellular component this GO :0005789 and endoplasmic reticulum membrane and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0006412 and translation and biological process this GO :0006468 and protein phosphorylation and biological process this GO :0006950 and response to stress and biological process this GO :0006970 and response to osmotic stress and biological process this GO :0006979 and response to oxidative stress and biological process this GO :0007165 and signal transduction and biological process this GO :0007166 and cell surface receptor signaling pathway and biological process this GO :0007169 and transmembrane receptor protein tyrosine kinase signaling pathway and biological process this GO :0007173 and epidermal growth factor receptor signaling pathway and biological process this GO :0007202 and activation of phospholipase C activity and biological process this GO :0007411 and axon guidance and biological process this GO :0007435 and salivary gland morphogenesis and biological process this GO :0007611 and learning or memory and biological process this GO :0007623 and circadian rhythm and biological process this GO :0008283 and cell proliferation and biological process this GO :0008284 and positive regulation of cell proliferation and biological process this GO :0008543 and fibroblast growth factor receptor signaling pathway and biological process this GO :0008544 and epidermis development and biological process this GO :0009986 and cell surface and cellular component this GO :0010008 and endosome membrane and cellular component this GO :0010960 and magnesium ion homeostasis and biological process this GO :0014070 and response to organic cyclic compound and biological process this GO :0016020 and membrane and cellular component this GO :0016021 and integral component of membrane and cellular component this GO :0016101 and diterpenoid metabolic process and biological process this GO :0016301 and kinase activity and molecular function this GO :0016323 and basolateral plasma membrane and cellular component this GO :0016324 and apical plasma membrane and cellular component this GO :0016337 and single organismal cell-cell adhesion and biological process this GO :0016772 and transferase activity, this GO :0001948 : glycoprotein binding, this GO :0001948 : glycoprotein binding and also this GO :0003682 : chromatin binding and also this GO :0003690 : double-stranded DNA binding and also this GO :0004672 : protein kinase activity and also this GO :0004709 : MAP kinase kinase kinase activity and also this GO :0004713 : protein tyrosine kinase activity and also this GO :0004714 : transmembrane receptor protein tyrosine kinase activity and also this GO :0004716 : receptor signaling protein tyrosine kinase activity and also this GO :0004871 : signal transducer activity and also this GO :0004888 : transmembrane signaling receptor activity and also this GO :0005006 : epidermal growth factor-activated receptor activity and also this GO :0005102 : receptor binding and also this GO :0005178 : integrin binding and also this GO :0005515 : protein binding and also this GO :0005524 : ATP binding and also this GO :0016301 : kinase activity and also this GO :0016772 : transferase activity, this GO :0003682 : chromatin binding, this GO :0003690 : double-stranded DNA binding, this GO :0004672 : protein kinase activity, this GO :0004709 : MAP kinase kinase kinase activity, this GO :0004713 : protein tyrosine kinase activity, this GO :0004714 : transmembrane receptor protein tyrosine kinase activity, this GO :0004716 : receptor signaling protein tyrosine kinase activity, this GO :0004871 : signal transducer activity, this GO :0004888 : transmembrane signaling receptor activity, this GO :0005006 : epidermal growth factor-activated receptor activity, this GO :0005102 : receptor binding, this GO :0005178 : integrin binding, this GO :0005515 : protein binding, this GO :0005524 : ATP binding, this GO :0016301 : kinase activity, this GO :0016772 : transferase activity, this GO :0019899 : enzyme binding, this GO :0019901 : protein kinase binding, this GO :0019903 : protein phosphatase binding, this GO :0030235 : nitric-oxide synthase regulator activity, this GO :0042802 : identical protein binding, this GO :0046982 : protein heterodimerization activity, this GO :0048408 : epidermal growth factor binding, this GO :0051015 : actin filament binding, transferase activity, transferring phosphorus-containing groups, transferring phosphorus-containing groups and also this GO :0019899 : enzyme binding and also this GO :0019901 : protein kinase binding and also this GO :0019903 : protein phosphatase binding and also this GO :0030235 : nitric-oxide synthase regulator activity and also this GO :0042802 : identical protein binding and also this GO :0046982 : protein heterodimerization activity and also this GO :0048408 : epidermal growth factor binding and also this GO :0051015 : actin filament binding, transferring phosphorus-containing groups and molecular function this GO :0018108 and peptidyl-tyrosine phosphorylation and biological process this GO :0019694 and alkanesulfonate metabolic process and biological process this GO :0019899 and enzyme binding and molecular function this GO :0019901 and protein kinase binding and molecular function this GO :0019903 and protein phosphatase binding and molecular function this GO :0021795 and cerebral cortex cell migration and biological process this GO :0023014 and signal transduction by phosphorylation and biological process this GO :0030122 and AP-2 adaptor complex and cellular component this GO :0030139 and endocytic vesicle and cellular component this GO :0030235 and nitric-oxide synthase regulator activity and molecular function this GO :0030324 and lung development and biological process this GO :0030335 and positive regulation of cell migration and biological process this GO :0031659 and positive regulation of cyclin-dependent protein kinase activity involved in G1/S and biological process this GO :0031965 and nuclear membrane and cellular component this GO :0032355 and response to estradiol and biological process this GO :0032930 and positive regulation of superoxide anion generation and biological process this GO :0033590 and response to cobalamin and biological process this GO :0033594 and response to hydroxyisoflavone and biological process this GO :0033993 and response to lipid and biological process this GO :0035413 and positive regulation of catenin import into nucleus and biological process this GO :0035556 and intracellular signal transduction and biological process this GO :0035690 and cellular response to drug and biological process this GO :0038095 and Fc-epsilon receptor signaling pathway and biological process this GO :0042059 and negative regulation of epidermal growth factor receptor signaling pathway and biological process this GO :0042127 and regulation of cell proliferation and biological process this GO :0042177 and negative regulation of protein catabolic process and biological process this GO :0042327 and positive regulation of phosphorylation and biological process this GO :0042698 and ovulation cycle and biological process this GO :0042743 and hydrogen peroxide metabolic process and biological process this GO :0042802 and identical protein binding and molecular function this GO :0043006 and activation of phospholipase A2 activity by calcium-mediated signaling and biological process this GO :0043066 and negative regulation of apoptotic process and biological process this GO :0043235 and receptor complex and cellular component this GO :0043406 and positive regulation of MAP kinase activity and biological process this GO :0043586 and tongue development and biological process this GO :0045087 and innate immune response and biological process this GO :0045121 and membrane raft and cellular component this GO :0045429 and positive regulation of nitric oxide biosynthetic process and biological process this GO :0045739 and positive regulation of DNA repair and biological process this GO :0045740 and positive regulation of DNA replication and biological process this GO :0045907 and positive regulation of vasoconstriction and biological process this GO :0045909 and positive regulation of vasodilation and biological process this GO :0045930 and negative regulation of mitotic cell cycle and biological process this GO :0045944 and positive regulation of transcription from RNA polymerase II promoter and biological process this GO :0046777 and protein autophosphorylation and biological process this GO :0046982 and protein heterodimerization activity and molecular function this GO :0048011 and neurotrophin TRK receptor signaling pathway and biological process this GO :0048015 and phosphatidylinositol-mediated signaling and biological process this GO :0048143 and astrocyte activation and biological process this GO :0048146 and positive regulation of fibroblast proliferation and biological process this GO :0048408 and epidermal growth factor binding and molecular function this GO :0048471 and perinuclear region of cytoplasm and cellular component this GO :0048546 and digestive tract morphogenesis and biological process this GO :0048661 and positive regulation of smooth muscle cell proliferation and biological process this GO :0048812 and neuron projection morphogenesis and biological process this GO :0050679 and positive regulation of epithelial cell proliferation and biological process this GO :0050729 and positive regulation of inflammatory response and biological process this GO :0050730 and regulation of peptidyl-tyrosine phosphorylation and biological process this GO :0050999 and regulation of nitric-oxide synthase activity and biological process this GO :0051015 and actin filament binding and molecular function this GO :0051205 and protein insertion into membrane and biological process this GO :0051592 and response to calcium ion and biological process this GO :0051897 and positive regulation of protein kinase B signaling and biological process this GO :0051968 and positive regulation of synaptic transmission, epidermal growth factor receptor |
| Identity: |
3236 |
| Gene: |
EGFR |
More about : EGFR |
| Long gene name: |
epidermal growth factor receptor |
| Synonyms gene: |
ERBB |
| Synonyms gene name: |
epidermal growth factor receptor (avian erythroblastic leukemia viral (v-erb-b) oncogene homolog) |
| Synonyms: |
ERBB1 |
| Synonyms name: |
erythroblastic leukemia viral (v-erb-b) oncogene homolog (avian) erb-b2 receptor tyrosine kinase 1 |
| Locus: |
7p11, 2 |
| Discovery year: |
1986-01-01 |
| Entrez gene record: |
1956 |
| Pubmed identfication: |
1505215 |
| RefSeq identity: |
NM_005228 |
| Classification: |
Erb-b2 receptor tyrosine kinases |
| Havana BLAST/BLAT: |
OTTHUMG00000023661 |
| Locus Specific Databases: |
LRG_304 |