| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
TCN2 |
| Specificity: |
This antibody reacts specifically with TCN2 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human TCN2/Transcobalamin II |
| Gene ID: |
6948 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
The genes encoding these proteins map to chromosome 11q11-q12 and 22q12, These plasma proteins are expressed in various tissues and secretions, Transcobalamin I is a constituent of secondary granules in neutrophils, respectively, while Transcobalamin II binds cobalamin and mediates its transport into cells, 2, Transcobalamin I (TCI) and Transcobalamin II (TCII) are secreted proteins belonging to the eukaryotic cobalamin transport proteins family and also to the vitamin B12-binding protein family |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
D22S676 D22S750 TC2 |
| Also known as: |
TCN2 Polyclonal Antibody |
| Other name: |
Anti-TCN2 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
TCN2 |
| Short name: |
Anti-TCN2 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-TCN2 (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
11653 |
| Gene: |
TCN2 |
More about : TCN2 |
| Long gene name: |
transcobalamin 2 |
| Synonyms gene name: |
macrocytic anemia transcobalamin II , transcobalamin II |
| Synonyms name: |
macrocytic anemia |
| Locus: |
22q12, 2 |
| Discovery year: |
2001-06-22 |
| Entrez gene record: |
6948 |
| Pubmed identfication: |
1708393 7742531 |
| RefSeq identity: |
NM_000355 |
| Havana BLAST/BLAT: |
OTTHUMG00000151095 |
| Locus Specific Databases: |
TCN2base: Mutation registry for Transcobalamin II deficiency LRG_116 |