| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
Titin |
| Specificity: |
This antibody reacts specifically with Titin |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human Titin (Ig-like 15 domain) |
| Gene ID: |
7273 |
| Swiss Prot: |
Q8WZ42 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
By providing connections at the level of individual microfilaments, In non-muscle cells, Might link the lamina network to chromatin or nuclear actin, The size and extensibility of the cross-links are the main determinants of sarcomere extensibility properties of muscle, it contributes to the fine balance of forces between the two halves of the sarcomere, or both during interphase, seems to play a role in chromosome condensation and chromosome segregation during mitosis, Key component in the assembly and functioning of vertebrate striated muscles |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
CMPD4 FLJ32040 TMD CMH9 LGMD2J MYLK5 |
| Also known as: |
Titin Polyclonal Antibody |
| Other name: |
Anti-Titin Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
Titin |
| Short name: |
Anti-Titin (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-Titin (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
12403 |
| Gene: |
TTN |
More about : TTN |
| Long gene name: |
titin |
| Synonyms gene: |
CMD1G |
| Synonyms gene name: |
cardiomyopathy, dilated 1G (autosomal dominant) |
| Locus: |
2q31, 2 |
| Discovery year: |
1991-06-07 |
| GenBank acession: |
X90568 |
| Entrez gene record: |
7273 |
| Pubmed identfication: |
2129545 10051295 |
| RefSeq identity: |
NM_133378 |
| Classification: |
Fibronectin type III domain containing I-set domain containing Immunoglobulin like domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000154448 |
| Locus Specific Databases: |
FHC Mutation Database TTN @ LOVD Leiden Muscular Dystrophy pages LRG_391 |