| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
BAALC |
| Specificity: |
This antibody reacts specifically with BAALC |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human BAALC |
| Gene ID: |
79870 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
BAALC interacts with CaMKII and is thought to play a role in synaptic function at postsynaptic lipid rafts, BAALC may be overexpressed in acute myeloid leukemia (AML), Expressed by hematopoetic and neural cells, Pfeiffer syndrome, Schizophrenia, The gene encoding BAALC maps to human chromosome 8, Trisomy 8, Waardenburg syndrome and some leukemias and lymphomas are thought to occur as a result of defects in specific genes that maps to chromosome 8, bipolar disorder, congenital hypothyroidism, houses more than 800 genes and is associated with a variety of diseases and malignancies, suggesting a role in tumorigenesis, which consists of nearly 146 million base pairs, BAALC is a 180 amino acid protein that localizes to both the membrane and the cytoplasm and exists as multiple alternatively spliced isoforms |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Also known as: |
BAALC Polyclonal Antibody |
| Other name: |
Anti-BAALC Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
BAALC |
| Short name: |
Anti-BAALC (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, cytoplasmic (polyclonal), antibody to-brain and acute leukemia |
| Alternative technique: |
polyclonals |
| Alternative to gene target: |
BAALC and IDBG-31581 and ENSG00000164929 and 79870, BT, Baalc and IDBG-136627 and ENSMUSG00000022296 and, Plasma membranes, cytoplasmic, this GO :0005737 and cytoplasm and cellular component this GO :0016020 and membrane and cellular component, 35965 and IDBG-645024 and ENSBTAG00000026242 and 614130, brain and acute leukemia |
| Identity: |
14333 |
| Gene: |
BAALC |
More about : BAALC |
| Long gene name: |
brain and acute leukemia, cytoplasmic |
| Locus: |
8q22, 3 |
| Discovery year: |
2001-01-26 |
| GenBank acession: |
AF363578 |
| Entrez gene record: |
79870 |
| Pubmed identfication: |
11707601 26050649 |
| Havana BLAST/BLAT: |
OTTHUMG00000164782 |