| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
ECRG4 |
| Specificity: |
This antibody reacts specifically with ECRG4 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human ECRG4/C2orf40 |
| Gene ID: |
84417 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
A number of genetic diseases are linked to genes on chromosome 2, Alstr syndrome is due to mutations in the ALMS1 gene, An extremely rare recessive genetic disorder, Belonging to the augurin family, ECRG4 is thought to be a hormone, Harlequin icthyosis, Interestingly, It has also been suggested that ECRG4 may act as a tumor suppressor, The gene that encodes ECRG4 maps to human chromosome 2, The lipid metabolic disorder sitosterolemia is associated with ABCG5 and ABCG8, a rare and morbid skin deformity, also known as augurin or C2orf40, chromosome 2 contains what appears to be a vestigial second centromere and vestigial telomeres which gives credence to the hypothesis that human chromosome 2 is the result of an ancient fusion of two ancestral chromosomes, is a 148 amino acid secreted protein, is associated with mutations in the ABCA12 gene, making up approximately 8% of the human genome, which consists of 237 million bases encoding over 1, 400 genes, ECRG4 |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
ECRG4 augurin |
| Also known as: |
ECRG4 Polyclonal Antibody |
| Other name: |
Anti-ECRG4 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
ECRG4 |
| Short name: |
Anti-ECRG4 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-ECRG4 (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
24642 |
| Gene: |
C2orf40 |
More about : C2orf40 |
| Long gene name: |
chromosome 2 open reading frame 40 |
| Synonyms name: |
esophageal cancer related gene 4 protein |
| Locus: |
2q12, 2 |
| Discovery year: |
2006-07-31 |
| GenBank acession: |
BC021742 |
| Entrez gene record: |
84417 |
| Pubmed identfication: |
12800218 |
| RefSeq identity: |
NM_032411 |
| Havana BLAST/BLAT: |
OTTHUMG00000130921 |