| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
ANKRD26 |
| Specificity: |
This antibody reacts specifically with ANKRD26 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human ANKRD26 |
| Gene ID: |
22852 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
ANKRD26 (ankyrin repeat domain-containing protein 26) is a 1709 amino acid protein that contains five ANK repeats, ANKRD26 is also expressed in the arcuate and ventromedial nuclei within the hypothalamus and in the ependyma and the circumventricular organs that act as an interface between the peripheral circulation and the brain, ANKRD26 may be phosphorylated upon DNA damage by Atm or ATR, Expressed at high level in many tissues, It is suggested that alterations in the gene encoding ANKRD26 may lead to obesity, Mutations of ankyrin genes lead to severe genetic diseases such as fatal cardiac arrhythmias and hereditary spherocytosis, Three isoforms of ANKRD26 exists due to alternative splicing events, including brain, kidney and heart, liver, Ankyrins are membrane adaptor molecules that play important roles in coupling integral membrane proteins to the spectrin-based cytoskeleton network |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
KIAA1074 |
| Also known as: |
ANKRD26 Polyclonal Antibody |
| Other name: |
Anti-ANKRD26 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
ANKRD26 |
| Short name: |
Anti-ANKRD26 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-ANKRD26 (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
29186 |
| Gene: |
ANKRD26 |
More about : ANKRD26 |
| Long gene name: |
ankyrin repeat domain 26 |
| Synonyms gene: |
THC2 |
| Synonyms gene name: |
thrombocytopenia 2 (autosomal dominant) |
| Locus: |
10p12, 1 |
| Discovery year: |
2004-02-04 |
| GenBank acession: |
AB028997 |
| Entrez gene record: |
22852 |
| Pubmed identfication: |
10470851 21211618 |
| Classification: |
Ankyrin repeat domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000017851 |
| Locus Specific Databases: |
LRG_605 |