| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
UFD1L |
| Specificity: |
This antibody reacts specifically with UFD1L |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human UFD1L |
| Gene ID: |
7353 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
The NPLOC4-UFD1L-VCP complex also regulates spindle disassembly at the end of mitosis and is necessary for the formation of a closed nuclear envelope, This complex, UFD1L gene hemizygosity is the cause of some developmental defects including DiGeorge syndrome (DGS), UFD1L has 2 named isoforms produced by alternative splicing, VCP and NPLOC4, also containing UFD1L, binds ubiquitinated proteins and is required for the export of misfolded proteins from the ER to the cytoplasm for disposal, velo-cardio-facial syndrome (VCFS) and Opitz G/BBB syndrome, UFD1L is a member of the UFD1 family of proteins and is a component of the ubiquitin-dependent proteolytic pathway which degrades ubiquitin fusion proteins |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
UFD1 |
| Also known as: |
UFD1L Polyclonal Antibody |
| Other name: |
Anti-UFD1L Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
UFD1L |
| Short name: |
Anti-UFD1L (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-UFD1L (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
12520 |
| Gene: |
UFD1L |
More about : UFD1L |
| Long gene name: |
ubiquitin fusion degradation 1 like (yeast) |
| Synonyms gene name: |
ubiquitin fusion degradation 1-like |
| Locus: |
22q11, 21 |
| Discovery year: |
1997-05-09 |
| GenBank acession: |
AJ239058 |
| Entrez gene record: |
7353 |
| Pubmed identfication: |
9063746 |
| Havana BLAST/BLAT: |
OTTHUMG00000150130 |