| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
PIBF1 |
| Specificity: |
This antibody reacts specifically with PIBF1 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human PIBF1/C13orf24 |
| Gene ID: |
10464 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Full-length PIBF is associated with the nucleus, In humans, In the presence of PIBF, Research suggests that PIBF functions as a transcription factor in its full-length form, The PIBF gene encodes a deduced hydrophilic 757-amino acid alpha-helical protein with an N-terminal signal sequence, a PEST sequence, a basic zipper sequence, a leucine zipper motif, a nuclear localization signal, an endoplasmic reticulum membrane retention signal, and many presumeed N-glycosylation and phosphorylation sites, natural killer (NK) cells inhibit the release of perforin from storage granules and therefore fail to lyse target cells, the amount of cells that express PIBF is significantly higher in healthy pregnant women than in women at risk for premature pregnancy termination, whereas secretion of shorter forms is induced by activation of the cell, while smaller forms may act as cytokines, PIBF is synthesized during pregnancy in response to progesterone by progesterone receptor-positive T lymphocytes (mostly gamma-delta T cells) |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
CEP90 |
| Also known as: |
PIBF1 Polyclonal Antibody |
| Other name: |
Anti-PIBF1 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
PIBF1 |
| Short name: |
Anti-PIBF1 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-PIBF1 (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
23352 |
| Gene: |
PIBF1 |
More about : PIBF1 |
| Long gene name: |
progesterone immunomodulatory binding factor 1 |
| Synonyms gene: |
C13orf24 |
| Synonyms gene name: |
chromosome 13 open reading frame 24 |
| Synonyms name: |
progesterone-induced blocking factor 1 |
| Locus: |
13q21, 1 , 33-q22 |
| Discovery year: |
2004-04-16 |
| GenBank acession: |
AF330046 |
| Entrez gene record: |
10464 |
| Pubmed identfication: |
11935316 |
| RefSeq identity: |
NM_006346 |
| Havana BLAST/BLAT: |
OTTHUMG00000017071 |