| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
AMPD3 |
| Specificity: |
This antibody reacts specifically with AMPD3 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human AMPD3 |
| Gene ID: |
272 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
AMPDDE is a metabolic disorder due to lack of activity of the erythrocyte isoform of AMP deaminase, Individuals with complete deficiency of erythrocyte AMP deaminase are healthy and have no hematologic disorders, It is a clinically asymptomatic condition characterized by a 50% increase in steady-state levels of ATP in affected cells, also known as erythrocyte AMP deaminase deficiency, AMP deaminase plays a critical role in energy metabolism, Involvement in diseaseDefects in AMPD3 are the cause of adenosine monophosphate deaminase deficiency erythrocyte type (AMPDDE) |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Also known as: |
AMPD3 Polyclonal Antibody |
| Other name: |
Anti-AMPD3 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
AMPD3 |
| Short name: |
Anti-AMPD3 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-AMPD3 (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
470 |
| Gene: |
AMPD3 |
More about : AMPD3 |
| Long gene name: |
adenosine monophosphate deaminase 3 |
| Synonyms gene name: |
adenosine monophosphate deaminase (isoform E) |
| Synonyms name: |
erythrocyte-specific AMP deaminase |
| Locus: |
11p15, 4 |
| Discovery year: |
1993-02-17 |
| GenBank acession: |
M84722 |
| Entrez gene record: |
272 |
| Pubmed identfication: |
1400401 |
| RefSeq identity: |
NM_000480 |
| Classification: |
Adenosine deaminase family |
| Havana BLAST/BLAT: |
OTTHUMG00000165682 |