| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
MEF2B |
| Specificity: |
This antibody reacts specifically with MEF2B |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human MEF2B |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
-2B, -2C, Differential regulation in the expression of the four transcripts implies functional distinction for each during embryogenesis and development, Each of these proteins binds to the MEF-2 target DNA sequence present in the regulatory regions of many muscle-specific genes, Four family members, Myf-5, The MEF-2 family represents a second class of DNA binding regulatory proteins, The myogenic basic helix-loop-helix proteins, The process of differentiation from mesodermal precursor cells to myoblasts has led to the discovery of a variety of tissue-specific factors that regulate muscle gene expression, These members bind as homo- and heterodimers to the MEF-2 site in the promoter region of affected genes, and -2D, and MRF4, and muscle cells, are one class of identified factors, arise from alternatively spliced transcripts, including MyoD, myogenin, neuronal cells, termed MEF-2A, The myocyte enhancer factor-2 (MEF-2) family of transcription factors associate with co-repessors or co-activators to regulate development and function of T cells |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
RSRFR2 |
| Also known as: |
MEF2B Polyclonal Antibody |
| Other name: |
Anti-MEF2B Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
MEF2B |
| Short name: |
Anti-MEF2B (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-MEF2B (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
6995 |
| Gene: |
MEF2B |
More about : MEF2B |
| Long gene name: |
myocyte enhancer factor 2B |
| Locus: |
19p13, 11 |
| Discovery year: |
1995-02-08 |
| GenBank acession: |
X63380 |
| Entrez gene record: |
100271849 |
| Pubmed identfication: |
1516833 8575763 |
| RefSeq identity: |
NM_005919 |
| Classification: |
Myocyte enhancer factor 2 proteins MADS box family |
| Havana BLAST/BLAT: |
OTTHUMG00000161595 |