| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
HSPB7 |
| Specificity: |
This antibody reacts specifically with HSPB7 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human HSPB7/cvHSP |
| Gene ID: |
27129 |
| Swiss Prot: |
Q9UBY9 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
HSP 60, HSP 70, HSPB7 (heat shock 27kDa protein family, Heat shock proteins (also known as molecular chaperones) fall into six general families: HSP 90, In response to muscle fiber transformation and in muscular dystrophy, Members of the sHSP family contain a conserved C-terminal ?crystallin domain and typically function in homo- or heteromeric complexes, The sHSPs bind to denatured proteins and are responsible for preventing the aggregation of these proteins, abundantly expressed proteins with diverse functions, also known as cvHSP (cardiovascular heat shock protein) or Heat shock protein beta-7, including the assembly and sequestering of multiprotein complexes, is a member of the small HSP (sHSP) family expressed in heart and skeletal muscle, member 7), suggesting that HSPB7 may be a useful target in therapeutic strategies for preventing age-related muscle wasting, the expression levels of HSPB7 are drastically increased, the immunophilins and the HSP 110 family, the small HSPs, transportation of nascent polypeptide chains across cellular membranes and regulation of protein folding, The heat shock proteins (HSPs) comprise a group of highly conserved |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
cvHSP |
| Also known as: |
HSPB7 Polyclonal Antibody |
| Other name: |
Anti-HSPB7 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
HSPB7 |
| Short name: |
Anti-HSPB7 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-HSPB7 (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
5249 |
| Gene: |
HSPB7 |
More about : HSPB7 |
| Long gene name: |
heat shock protein family B (small) member 7 |
| Synonyms gene name: |
heat shock 27kD protein family, member 7 (cardiovascular) , member 7 (cardiovascular) heat shock 27kDa protein family |
| Locus: |
1p36, 13 |
| Discovery year: |
2000-01-26 |
| GenBank acession: |
AF155908 |
| Entrez gene record: |
27129 |
| Pubmed identfication: |
10593960 |
| RefSeq identity: |
NM_014424 |
| Classification: |
Small heat shock proteins |
| Havana BLAST/BLAT: |
OTTHUMG00000009531 |