| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
PSMD7 |
| Specificity: |
This antibody reacts specifically with PSMD7 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human PSMD7 |
| Gene ID: |
5713 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits, A pseudogene has been identified on chromosome 17, An essential function of a modified proteasome, Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway, The 19S regulator is composed of a base, The 20S core is composed of 4 rings of 28 non-identical subunits, This gene encodes a non-ATPase subunit of the 19S regulator, a 20S core and a 19S regulator, and a lid, is the processing of class I MHC peptides, the immunoproteasome, which contains 6 ATPase subunits and 2 non-ATPase subunits, which contains up to 10 non-ATPase subunits, The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
S12 P40 MOV34 Rpn8 |
| Also known as: |
PSMD7 Polyclonal Antibody |
| Other name: |
Anti-PSMD7 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
PSMD7 |
| Short name: |
Anti-PSMD7 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
7 (polyclonal), ALEXA Fluor 594, macropain) 26S subunit, non-ATPase, antibody to-proteasome (prosome |
| Alternative technique: |
polyclonals |
| Alternative to gene target: |
7, MOV34 and P40 and Rpn8 and S12, PSMD7 and IDBG-41946 and ENSG00000103035 and 5713, PSMD7 and IDBG-634622 and ENSBTAG00000018425 and 512456, Psmd7 and IDBG-190966 and ENSMUSG00000039067 and 17463, TAP-dependent and biological process this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005654 and nucleoplasm and cellular component this GO :0005829 and cytosol and cellular component this GO :0005838 and proteasome regulatory particle and cellular component this GO :0006521 and regulation of cellular amino acid metabolic process and biological process this GO :0006915 and apoptotic process and biological process this GO :0006977 and DNA damage response, macropain) 26S subunit, non-ATPase, nuclei, protein binding, signal transduction by p53 class mediator resulting in cell cycle arrest and biological process this GO :0010467 and gene expression and biological process this GO :0016020 and membrane and cellular component this GO :0016032 and viral process and biological process this GO :0016070 and RNA metabolic process and biological process this GO :0016071 and mRNA metabolic process and biological process this GO :0031145 and anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process and biological process this GO :0034641 and cellular nitrogen compound metabolic process and biological process this GO :0042590 and antigen processing and presentation of exogenous peptide antigen via MHC class I and biological process this GO :0042981 and regulation of apoptotic process and biological process this GO :0043066 and negative regulation of apoptotic process and biological process this GO :0044281 and small molecule metabolic process and biological process this GO :0051436 and negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle and biological process this GO :0051437 and positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle and biological process this GO :0051439 and regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle and biological process this GO :0070062 and extracellular vesicular exosome and cellular component, this GO :0000082 and G1/S transition of mitotic cell cycle and biological process this GO :0000209 and protein polyubiquitination and biological process this GO :0000278 and mitotic cell cycle and biological process this GO :0000502 and proteasome complex and cellular component this GO :0002474 and antigen processing and presentation of peptide antigen via MHC class I and biological process this GO :0002479 and antigen processing and presentation of exogenous peptide antigen via MHC class I, this GO :0005515 : protein binding, this GO :0005515 : protein binding, proteasome (prosome |
| Identity: |
9565 |
| Gene: |
PSMD7 |
More about : PSMD7 |
| Long gene name: |
non-ATPase 7 , proteasome 26S subunit |
| Synonyms gene name: |
7 , 7 (Mov34 homolog) proteasome (prosome, macropain) 26S subunit, macropain) 26S subunit, non-ATPase, non-ATPase, proteasome (prosome |
| Synonyms name: |
Mov34 homolog |
| Locus: |
16q23, 1 |
| Discovery year: |
1991-06-05 |
| GenBank acession: |
D50063 |
| Entrez gene record: |
5713 |
| Pubmed identfication: |
7755639 |
| RefSeq identity: |
NM_002811 |
| Classification: |
Proteasome |
| Havana BLAST/BLAT: |
OTTHUMG00000137601 |