| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
Proteasome 20S C2 |
| Specificity: |
This antibody reacts specifically with Proteasome 20S C2 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human Proteasome 20S C2 |
| Gene ID: |
5682 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
20S Proteasome ?, At specific stages of development, In eukaryotic cells, The entire proteasome is composed of at least 15 non-identical subunits which form a highly-ordered ring-shaped structure, also designated macropain subunit C2 or PROS-30, embryo- and tissue-specific components of the 26S proteasome form, facilitating proteolysis, is a prosomal protein involved in a non-lysosomal ATP/ubiquitin-dependent proteolytic pathway, selective breakdown of cellular proteins is ensured by their ubiquitination and subsequent degradation by the 26S proteasome, transcription factors and tumor suppressors, Ubiquitin-dependent proteolysis mediates selective destruction of various cell cycle regulators |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
30 kDa prosomal protein, HC 2, HC2, Macropain subunit C2, Macropain subunit nu, Multicatalytic endopeptidase complex subunit C2, NU antibody PROS 30, PROS-30, PROS30, PSA1_HUMAN, PSC 2, PSC2, PSMA 1, Proteasome alpha 1 subunit, Proteasome component C2, Proteasome nu chain, Proteasome prosome macropain subunit alpha type 1, Proteasome subunit alpha type 1, Proteasome subunit alpha type I, Proteasome subunit alpha type-1, Proteasome subunit nu, Protein P30 33K, psmA1, ±, 1, 20S Proteasome Î |
| Also known as: |
Proteasome 20S C2 Polyclonal Antibody |
| Other name: |
Anti-Proteasome 20S C2 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
Proteasome 20S C2 |
| Short name: |
Anti-Proteasome 20S C2 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-protein degradation aggregate 20S complement component 2 (polyclonal) |
| Alternative technique: |
polyclonals |
| Alternative to gene target: |
ARMD14 and CO2, C2 and IDBG-124824 and ENSG00000166278 and 101928623, C2 and IDBG-174547 and ENSMUSG00000024371 and 12263, C2 and IDBG-633680 and ENSBTAG00000007450 and 515440, Extracellular, classical pathway and biological process this GO :0007584 and response to nutrient and biological process this GO :0030449 and regulation of complement activation and biological process this GO :0045087 and innate immune response and biological process this GO :2000427 and positive regulation of apoptotic cell clearance and biological process, protein binding, this GO :0003824 and catalytic activity and molecular function this GO :0004252 and serine-type endopeptidase activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005576 and extracellular region and cellular component this GO :0005615 and extracellular space and cellular component this GO :0006508 and proteolysis and biological process this GO :0006956 and complement activation and biological process this GO :0006958 and complement activation, this GO :0003824 : catalytic activity, this GO :0003824 : catalytic activity and also this GO :0004252 : serine-type endopeptidase activity and also this GO :0005515 : protein binding, this GO :0004252 : serine-type endopeptidase activity, this GO :0005515 : protein binding, 717, complement component 2 |