| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
PACRG |
| Specificity: |
This antibody reacts specifically with PACRG |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human PACRG |
| Gene ID: |
135138 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
It is thought to be co-transcribed with parkin by a bi-directional promoter between the two genes, Northern blot analysis detects PACRG expression in all tissues examined except placenta, PACRG and Parkin are attached in a head-to-head arrangement on opposite DNA strands and share a common 5' flanking promoter region, Possession of two or more of the 17 risk alleles is highly predictive of leprosy, The PACRG gene maps to chromosome 6q26, Using a positional cloning strategy in 197 Vietnamese leprosy simplex families (i, families with two unaffected parents and one affected child), in reverse orientation on the chromosome, significant connections between leprosy and 17 markers in the 5' regulatory region that PARK2 and PACRG share were observed, PACRG is a gene located very close to parkin, The deduced 257 amino acid protein PACRG (Parkin co-regulated gene) shows potential links to the ubiquitin/proteasome system, e |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
PARK2CRG FLJ32724 Glup HAK005771 |
| Also known as: |
PACRG Polyclonal Antibody |
| Other name: |
Anti-PACRG Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
PACRG |
| Short name: |
Anti-PACRG (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-PACRG (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
19152 |
| Gene: |
PACRG |
More about : PACRG |
| Long gene name: |
parkin coregulated |
| Synonyms gene name: |
PARK2 coregulated |
| Locus: |
6q26 |
| Discovery year: |
2003-06-25 |
| GenBank acession: |
AK057286 |
| Entrez gene record: |
135138 |
| Pubmed identfication: |
12547187 |
| RefSeq identity: |
NM_152410 |
| Havana BLAST/BLAT: |
OTTHUMG00000016116 |