| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
CREG1 |
| Specificity: |
This antibody reacts specifically with CREG1 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human CREG1 |
| Gene ID: |
8804 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Binding sites for E2F, CREG (cellular repressor of E1A-stimulated genes) is a cellular protein that antagonizes transcriptional activation and cellular transformation by E1A, CREG activity may contribute to the transcriptional control of cell growth and differentiation, CREG is a secreted glycoprotein which enhances differentiation of mouse embryonic stem cells and human NTERA-2 cells, CREG is broadly expressed in adult tissues and is regulated during embryonic development, CREG was initially isolated in a yeast two-hybrid screen due to its interaction with the TATA-binding protein, TBP, a key transcriptional reg-ulator of cell cycle progression, and CREG was shown to inhibit activation by E2F, are required for repression of the adeno-virus E2 promoter by CREG, The adenovirus E1A protein both activates and represses gene expression to promote cellular proliferation and inhibit differentiation |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Also known as: |
CREG1 Polyclonal Antibody |
| Other name: |
Anti-CREG1 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
CREG1 |
| Short name: |
Anti-CREG1 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-CREG1 (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
2351 |
| Gene: |
CREG1 |
More about : CREG1 |
| Long gene name: |
cellular repressor of E1A stimulated genes 1 |
| Synonyms gene: |
CREG |
| Synonyms gene name: |
cellular repressor of E1A-stimulated genes |
| Locus: |
1q24, 2 |
| Discovery year: |
1999-06-24 |
| GenBank acession: |
AF084523 |
| Entrez gene record: |
8804 |
| Pubmed identfication: |
9710587 |
| RefSeq identity: |
NM_003851 |
| Havana BLAST/BLAT: |
OTTHUMG00000034682 |