| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
Cystatin D |
| Specificity: |
This antibody reacts specifically with Cystatin D |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human Cystatin D |
| Gene ID: |
1473 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
All true cystatins inhibit cysteine peptidases of the papain family, Cystatin C is a related protein which is expressed in brain, Cystatin D protects against proteinases in the oral cavity, Cystatin S and SN can also be expressed in tears, Cystatin SA, Cystatins A and B (type 1) are mainly intracellular, D, E/M, F, G, High molecular weight kininogen (Kininogen HC) and low molecular weight kininogen (Kininogen LC) have varied roles, S, SN and SA cystatins are extracellular (type 2), The fetuins, and some also inhibit legumain family enzymes, and the kininogens are type 3 cystatins which are intravascular proteins, are secretable proteins that influence osteogenesis and bone resorption, cystatin S and cystatin SN are found primarily in saliva, cystatins C, epididymis and vas deferens, ovary, part of the cystatin superfamily, regulation of the insulin and hepatocyte growth factor receptors and the response to systemic inflammation, such as cathepsins, though they both inhibit the thrombin- and plasmin-induced aggregation of thrombocytes, thymus, urine and seminal fluid, while Cystatin E/M and F moderate the inhibition of cathepsin proteins, The cystatin superfamily is a well-established family of cysteine protease inhibitors |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Also known as: |
Cystatin D Polyclonal Antibody |
| Other name: |
Anti-Cystatin D Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
Cystatin D |
| Short name: |
Anti-Cystatin D (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-Cystatin D (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
2477 |
| Gene: |
CST5 |
More about : CST5 |
| Long gene name: |
cystatin D |
| Locus: |
20p11, 21 |
| Discovery year: |
1993-01-20 |
| Entrez gene record: |
1473 |
| Pubmed identfication: |
1939105 |
| RefSeq identity: |
NM_001900 |
| Classification: |
Cystatins, type 2 |
| Havana BLAST/BLAT: |
OTTHUMG00000032089 |