| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
IGSF3 |
| Specificity: |
This antibody reacts specifically with IGSF3 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Subcellular locations: |
Extracellular |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human IGSF3 |
| Gene ID: |
3321 |
| Applications: |
IF(IHC-P), FCM |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200), FCM(1:20-100) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Based on its subcellular localization and the presence of the eight Ig domains, Despite the structural similarities between IGSF3 and CD101, IGSF3 exhibits strong sequence and structural similarity to CD101 (32% identity), IGSF3 is hypothesized to function as a surface receptor or as a cell adhesion molecule, IGSF3 is not expressed in peripheral blood lymphocytes and does not appear to participate in an immune function, IGSF3 localizes to the membrane and contains an N-terminal signal peptide, Widely expressed with predominant expression in kidney, a leukocyte surface protein with seven Ig domains that is believed to play a role in T-cell activation, also known as V8 or EWI-3, eight immunoglobulin (Ig) domains and a transmembrane segment, is a 1, placenta and lung, 214 amino acid protein, IGSF3 |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
V8 EWI-3 MGC117164 |
| Also known as: |
IGSF3 Polyclonal Antibody |
| Other name: |
Anti-IGSF3 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
IGSF3 |
| Short name: |
Anti-IGSF3 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, member 3 (polyclonal), antibody to-immunoglobulin superfamily |
| Alternative technique: |
polyclonals |
| Alternative to gene target: |
EWI-3 and V8, IGSF3 and IDBG-101405 and ENSG00000143061 and 3321, IGSF3 and IDBG-634471 and ENSBTAG00000004849 and 530939, Igsf3 and IDBG-179763 and ENSMUSG00000042035 and 78908, Plasma membranes, member 3, protein binding, this GO :0003674 and molecular function and molecular function this GO :0005515 and protein binding and molecular function this GO :0005575 and cellular component and cellular component this GO :0016021 and integral component of membrane and cellular component this GO :0032808 and lacrimal gland development and biological process, this GO :0003674 : molecular_function, this GO :0003674 : molecular_function and also this GO :0005515 : protein binding, this GO :0005515 : protein binding, immunoglobulin superfamily |
| Identity: |
5950 |
| Gene: |
IGSF3 |
More about : IGSF3 |
| Long gene name: |
immunoglobulin superfamily member 3 |
| Synonyms gene name: |
immunoglobulin superfamily, member 3 |
| Locus: |
1p13, 1 |
| Discovery year: |
1998-08-13 |
| GenBank acession: |
AF031174 |
| Entrez gene record: |
3321 |
| Pubmed identfication: |
9790749 |
| RefSeq identity: |
NM_001542 |
| Classification: |
V-set domain containing Immunoglobulin like domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000022751 |