| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
TRIM3 |
| Specificity: |
This antibody reacts specifically with TRIM3 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human TRIM3 |
| Gene ID: |
10612 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
å, Localized to cytoplasmic filaments, Members of the RBCC family have an N-terminal RING finger, RING finger protein 97 (RNF97) or brain-expressed RING finger protein (BERP), Specifically, TRIM3 has been shown to interact with å, These associations suggest that TRIM3 may play a role in cell motility and cargo transport, Three named isoforms of TRIM3 exist as a result of alternative splicing events, a leucine coiled-coil region and a variable C-terminal domain, also known as RING finger protein 22 (RNF22), also known as the RING-B-box coiled-coil (RBCC) family, and the C-terminal tail of Myosin V interacts with with the unique C-terminal â, followed by one or two zinc-binding domains (B-box domains), is a 744 amino acid member of the TRIM family, two proteins associated with the actin cytoskeleton, &circ, «, -actinin-4 and myosin V, -actinin-4 interacts with the RBCC domain of TRIM3, -propeller domain of TRIM3, Tripartite motif-containing protein 3 (TRIM3) |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
HAC1 BERP RNF97 |
| Also known as: |
TRIM3 Polyclonal Antibody |
| Other name: |
Anti- TRIM3 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
TRIM3 |
| Short name: |
Anti- TRIM3 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, Antibody to TRIM3 (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
10064 |
| Gene: |
TRIM3 |
More about : TRIM3 |
| Long gene name: |
tripartite motif containing 3 |
| Synonyms gene: |
RNF22 |
| Synonyms gene name: |
tripartite motif-containing 3 |
| Synonyms name: |
ring finger protein 22 brain expressed ring finger tripartite motif protein TRIM3 |
| Locus: |
11p15, 4 |
| Discovery year: |
2000-07-31 |
| GenBank acession: |
AF045239 |
| Entrez gene record: |
10612 |
| Pubmed identfication: |
10391919 |
| RefSeq identity: |
NM_006458 |
| Classification: |
Tripartite motif containing Ring finger proteins |
| Havana BLAST/BLAT: |
OTTHUMG00000133405 |