| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
TRIM35 |
| Specificity: |
This antibody reacts specifically with TRIM35 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human TRIM35 |
| Gene ID: |
23087 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
TRIM35 may play a role as a tumor suppressor and is implicated in the cell death mechanism, The TRIM motif includes three zinc-binding domains, There are two named isoforms, a B-box type 1, a B-box type 2 and a coiled-coil region, a RING, TRIM35 is a member of the tripartite motif (TRIM) family |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
KIAA1098 MAIR HLS5 |
| Also known as: |
TRIM35 Polyclonal Antibody |
| Other name: |
Anti-TRIM35 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
TRIM35 |
| Short name: |
Anti-TRIM35 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-tripartite motif containing 35 (polyclonal) |
| Alternative technique: |
polyclonals |
| Alternative to gene target: |
HLS5 and MAIR, TRIM35 and IDBG-13769 and ENSG00000104228 and 23087, TRIM35 and IDBG-635648 and ENSBTAG00000009958 and 518310, Trim35 and IDBG-175374 and ENSMUSG00000022043 and 66854, metal ion binding, nuclei, this GO :0003674 and molecular function and molecular function this GO :0005515 and protein binding and molecular function this GO :0005622 and intracellular and cellular component this GO :0005634 and nucleus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0006915 and apoptotic process and biological process this GO :0008270 and zinc ion binding and molecular function this GO :0008285 and negative regulation of cell proliferation and biological process this GO :0043065 and positive regulation of apoptotic process and biological process this GO :0045087 and innate immune response and biological process this GO :0045930 and negative regulation of mitotic cell cycle and biological process this GO :0046872 and metal ion binding and molecular function this GO :1902187 and negative regulation of viral release from host cell and biological process, this GO :0003674 : molecular_function, this GO :0003674 : molecular_function and also this GO :0005515 : protein binding and also this GO :0008270 : zinc ion binding and also this GO :0046872 : metal ion binding, this GO :0005515 : protein binding, this GO :0008270 : zinc ion binding, this GO :0046872 : metal ion binding, tripartite motif containing 35 |
| Identity: |
16285 |
| Gene: |
TRIM35 |
More about : TRIM35 |
| Long gene name: |
tripartite motif containing 35 |
| Synonyms gene name: |
tripartite motif-containing 35 |
| Locus: |
8p21, 2 |
| Discovery year: |
2001-11-21 |
| GenBank acession: |
AB029021 |
| Entrez gene record: |
23087 |
| Pubmed identfication: |
11331580 14662771 12692137 |
| RefSeq identity: |
NM_171982 |
| Classification: |
Tripartite motif containing Ring finger proteins |
| Havana BLAST/BLAT: |
OTTHUMG00000102047 |