| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
AGXT2L2 |
| Specificity: |
This antibody reacts specifically with AGXT2L2 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human AGXT2L2 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
AGXT2 protects from asymmetric dimethylarginine (ADMA)-induced inhibition in nitric oxide (NO) production, AGXT2L2 (alanine-glyoxylate aminotransferase 2-like 2) is a 450 amino acid pyridoxal phosphate that exists as a homotetramer, AGXT2L2 localizes to the mitochondria and exists as three alternatively spliced isoforms, AGXT2L2 may have similar functions as AGXT2, Belonging to the class-III pyridoxal-phosphate-dependent aminotransferase family, Elevated blood concentrations of ADMA, Encoded by a gene located on human chromosome 5q35, a methyl derivate of the amino acid arginine and an endogenous inhibitor of nitric oxide (NO) synthase, catalyze the conversion of glyoxylate to glycine using L-alanine as the amino donor, congestive heart failure and atherosclerosis, hypertension, is produced by the physiological degradation of methylated proteins and is found in association with diabetes, such as AGXT2, 3, Members of the class-III pyridoxal-phosphate-dependent aminotransferase family |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
MGC15875 |
| Also known as: |
AGXT2L2 Polyclonal Antibody |
| Other name: |
Anti-AGXT2L2 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
AGXT2L2 |
| Short name: |
Anti-AGXT2L2 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-AGXT2L2 (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
28249 |
| Gene: |
PHYKPL |
More about : PHYKPL |
| Long gene name: |
5-phosphohydroxy-L-lysine phospho-lyase |
| Synonyms gene: |
AGXT2L2 |
| Synonyms gene name: |
alanine-glyoxylate aminotransferase 2-like 2 |
| Synonyms name: |
5-phosphonooxy-L-lysine phospho-lyase |
| Locus: |
5q35, 3 |
| Discovery year: |
2006-08-11 |
| GenBank acession: |
BC037567 |
| Entrez gene record: |
85007 |
| Pubmed identfication: |
22241472 |
| RefSeq identity: |
NM_032921 |
| Havana BLAST/BLAT: |
OTTHUMG00000130892 |