| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
PDXK |
| Specificity: |
This antibody reacts specifically with PDXK |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human PDXK |
| Gene ID: |
8566 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
PDXK, PLP acts as a coenzyme and functions to maintain homeostasis, Pyridoxal kinase is a 312-amino acid cytoplasmic protein that may act as a homodimer and is expressed ubiquitously, The optimum pH for pyridoxal kinase is between 5, There are three known isoforms of pyridoxal kinase, a genetic disorder that has been mapped to the same region on chromosome 21, a step necessary for the conversion of vitamin B6 to pyridoxal 5â, and isoform 3 expression is observed in adult testis and spermatozoa, maps to chromosome 21q22, phosphate (PLP), the active form of vitamin B6, the gene that encodes the pyridoxal kinase protein, &euro, &trade, 3 and may be a candidate gene for autoimmune polyglandular disease type 1, 5 and 6, Pyridoxal kinase belongs to the pyridoxine kinase family and phosphorylates vitamin B6 |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
PNK PKH FLJ21324 PRED79 FLJ31940 MGC15873 |
| Also known as: |
PDXK Polyclonal Antibody |
| Other name: |
Anti-PDXK Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
PDXK |
| Short name: |
Anti-PDXK (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-PDXK (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
8819 |
| Gene: |
PDXK |
More about : PDXK |
| Long gene name: |
pyridoxal kinase |
| Synonyms gene: |
C21orf97 C21orf124 |
| Synonyms gene name: |
chromosome 21 open reading frame 97 chromosome 21 open reading frame 124 pyridoxal (pyridoxine, vitamin B6) kinase |
| Locus: |
21q22, 3 |
| Discovery year: |
1998-12-03 |
| GenBank acession: |
U89606 |
| Entrez gene record: |
8566 |
| Pubmed identfication: |
9099727 |
| RefSeq identity: |
NM_003681 |
| Havana BLAST/BLAT: |
OTTHUMG00000086870 |