| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
Connexin 43 |
| Specificity: |
This antibody reacts specifically with Connexin 43 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human Connexin 43 |
| Gene ID: |
2697 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
A related intronless pseudogene has been mapped to chromosome 5, Mutations in this gene have been associated with oculodentodigital dysplasia and heart malformations, The encoded protein is a component of gap junctions, The encoded protein is the major protein of gap junctions in the heart that are thought to have a crucial role in the synchronized contraction of the heart and in embryonic development, [provided by RefSeq], which are composed of arrays of intercellular channels that provide a route for the diffusion of low molecular weight materials from cell to cell, This gene is a member of the connexin gene family |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
CX43 ODD ODOD SDTY3 |
| Also known as: |
Connexin 43 Polyclonal Antibody |
| Other name: |
Anti-Connexin 43 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
Connexin 43 |
| Short name: |
Anti-Connexin 43 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-Connexin 43 (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
4274 |
| Gene: |
GJA1 |
More about : GJA1 |
| Long gene name: |
gap junction protein alpha 1 |
| Synonyms gene: |
ODDD GJAL |
| Synonyms gene name: |
43kDa , 43kDa (connexin 43) gap junction protein, alpha 1, alpha 1, alpha-like gap junction protein, gap junction protein |
| Synonyms name: |
oculodentodigital dysplasia (syndactyly type III) connexin 43 |
| Locus: |
6q22, 31 |
| Discovery year: |
1990-08-03 |
| GenBank acession: |
BC026329 |
| Entrez gene record: |
2697 |
| Pubmed identfication: |
10331943 1646158 |
| RefSeq identity: |
NM_000165 |
| Classification: |
Gap junction proteins |
| Havana BLAST/BLAT: |
OTTHUMG00000015479 |
| Locus Specific Databases: |
Hereditary Hearing Loss Homepage |