| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
Viperin |
| Specificity: |
This antibody reacts specifically with Viperin |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human Viperin/RSAD2 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Additionally, Cytomegalovirus and HIV-1, Localized to the cytosolic side of the endoplasmic reticulum and relocated to the Golgi apparatus upon viral infection, Overexpression of RSAD2 leads to abnormal lipid accumulation that is associated with atherosclerosis, RSAD2 can bind to and inactivate FDPS (an enzyme that is crucial for the synthesis of cholesterol and geranylated and farnesylated proteins), RSAD2 is thought to prevent viral budding by disrupting lipid rafts at the plasma membrane and supporting the Interferon-induced antiviral state of the cell, a chronic inflammatory disease characterized by hardened arteries, thereby playing a role in lipid synthesis, RSAD2 is a 361 amino acid protein that is involved in antiviral defense against pathogens such as Hep C |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
cig5 viperin vig1 |
| Also known as: |
Viperin Polyclonal Antibody |
| Other name: |
Anti-Viperin Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
Viperin |
| Short name: |
Anti-Viperin (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-Viperin (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
30908 |
| Gene: |
RSAD2 |
More about : RSAD2 |
| Long gene name: |
radical S-adenosyl methionine domain containing 2 |
| Locus: |
2p25, 2 |
| Discovery year: |
2004-11-08 |
| GenBank acession: |
AF442151 |
| Entrez gene record: |
91543 |
| Pubmed identfication: |
11752458 |
| RefSeq identity: |
NM_080657 |
| Havana BLAST/BLAT: |
OTTHUMG00000090352 |