| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
GPR7 |
| Specificity: |
This antibody reacts specifically with GPR7 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human GPR7 |
| Gene ID: |
2831 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
GPR7 deficient mice develop an adult-onset obese phenotype that progressively worsens with age and is exacerbated when fed a high-fat diet, In response to NPW and NPB, The genes encoding human GPR7 and GPR8 map to chromosomes 10q11, They both show high expression in brain and in particular in hypothalamus, and have been characterized as receptors for neuropeptide W (NPW) and neuropeptide B (NPB), respectively, they play a role in the regulation of feeding behavior, 1 and 10q13, 2-q21, 3, The two G protein-coupled receptors GPR7 and GPR8 display high similarity to each other |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Also known as: |
GPR7 Polyclonal Antibody |
| Other name: |
Anti-GPR7 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
GPR7 |
| Short name: |
Anti-GPR7 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-GPR7 (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
4522 |
| Gene: |
NPBWR1 |
More about : NPBWR1 |
| Long gene name: |
neuropeptides B and W receptor 1 |
| Synonyms gene: |
GPR7 |
| Synonyms gene name: |
G protein-coupled receptor 7 neuropeptides B/W receptor 1 |
| Locus: |
8q11, 23 |
| Discovery year: |
1994-07-25 |
| GenBank acession: |
BC033145 |
| Entrez gene record: |
2831 |
| Pubmed identfication: |
7590751 12401809 |
| RefSeq identity: |
NM_005285 |
| Classification: |
Neuropeptide receptors |
| Havana BLAST/BLAT: |
OTTHUMG00000164275 |