| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
FSIP1 |
| Specificity: |
This antibody reacts specifically with FSIP1 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human FSIP1 |
| Gene ID: |
161835 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
A member of the FSIP1 family, Angelman and Prader-Willi syndromes are associated with loss of function or deletion of genes in the 15q11-q13 region, Encoding more than 700 genes, FSIP1 is encoded by a gene that maps to human chromosome 15q14 and mouse chromosome 2 E5, In cases of Prader-Willi syndrome, In the case of Angelman syndrome, Marfan syndrome is associated with chromosome 15 through the FBN1 gene, Tay-Sachs disease is a lethal disorder associated with mutations of the HEXA gene, chromosome 15 is made up of approximately 106 million base pairs and is about 3% of the human genome, there is a partial or complete deletion of this region from the paternal copy of chromosome 15, this loss is due to inactivity of the maternal 15q11-q13 encoded UBE3A gene in the brain by either chromosomal deletion or mutation, which is encoded by chromosome 15, FSIP1 is a 581 amino acid protein that is expressed in airway epithelium |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
FLJ35989 |
| Also known as: |
FSIP1 Polyclonal Antibody |
| Other name: |
Anti-FSIP1 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
FSIP1 |
| Short name: |
Anti-FSIP1 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-FSIP1 (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
21674 |
| Gene: |
FSIP1 |
More about : FSIP1 |
| Long gene name: |
fibrous sheath interacting protein 1 |
| Locus: |
15q14 |
| Discovery year: |
2004-06-21 |
| GenBank acession: |
BC045191 |
| Entrez gene record: |
161835 |
| Pubmed identfication: |
14702039 |
| RefSeq identity: |
NM_152597 |
| Havana BLAST/BLAT: |
OTTHUMG00000172456 |