| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
IGF2BP2 |
| Specificity: |
This antibody reacts specifically with IGF2BP2 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human IGF2BP2/IMP2 |
| Gene ID: |
10644 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Defects in IGF2BP2 are thought to be associated with susceptibility to type 2 diabetes mellitus, IGF2BP2 is an RNA binding protein which may be involved in the regulation of mRNA translation and may also function to control the spatial localization of target mRNAs, IGF2BP2 is expressed in a variety of tissues including heart, IMP-2 (IGF-II mRNA-binding protein 2), VICKZ family member 2 or hepatocellular carcinoma autoantigen p62 and is a 556 amino acid protein, against IGF2BP2 have been detected in patients with HCC (hepatocellular carcinoma), fetal liver, kidney, lung, pancreas, placenta, skeletal muscle, suggesting that IGF2BP2 may have a role in the pathogenesis of HCC, thymus and gonadal cells, IGF2BP2 (insulin-like growth factor 2 mRNA binding protein 2) is also known as IGF2 mRNA-binding protein 2 |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
IMP-2 |
| Also known as: |
IGF2BP2 Polyclonal Antibody |
| Other name: |
Anti-IGF2BP2 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
IGF2BP2 |
| Short name: |
Anti-IGF2BP2 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-insulin-like growth factor 2 messenger RNA binding protein 2 (polyclonal) |
| Alternative technique: |
polyclonals |
| Alternative to gene target: |
IGF2BP2 and IDBG-634762 and ENSBTAG00000007666 and 519028, IGF2BP2 and IDBG-68594 and ENSG00000073792 and 10644, IMP-2 and IMP2 and VICKZ2, Igf2bp2 and IDBG-147890 and ENSMUSG00000033581 and 319765, mRNA 5'-UTR binding, nuclei, this GO :0000166 and nucleotide binding and molecular function this GO :0003676 and nucleic acid binding and molecular function this GO :0003723 and RNA binding and molecular function this GO :0003729 and mRNA binding and molecular function this GO :0003730 and mRNA 3'-UTR binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005829 and cytosol and cellular component this GO :0005856 and cytoskeleton and cellular component this GO :0009653 and anatomical structure morphogenesis and biological process this GO :0010467 and gene expression and biological process this GO :0017148 and negative regulation of translation and biological process this GO :0042035 and regulation of cytokine biosynthetic process and biological process this GO :0044822 and poly(A) RNA binding and molecular function this GO :0045182 and translation regulator activity and molecular function this GO :0048027 and mRNA 5'-UTR binding and molecular function this GO :0051028 and mRNA transport and biological process, this GO :0000166 : nucleotide binding, this GO :0000166 : nucleotide binding and also this GO :0003676 : nucleic acid binding and also this GO :0003723 : RNA binding and also this GO :0003729 : mRNA binding and also this GO :0003730 : mRNA 3'-UTR binding and also this GO :0005515 : protein binding and also this GO :0044822 : poly(A) RNA binding and also this GO :0045182 : translation regulator activity and also this GO :0048027 : mRNA 5'-UTR binding, this GO :0003676 : nucleic acid binding, this GO :0003723 : RNA binding, this GO :0003729 : mRNA binding, this GO :0003730 : mRNA 3'-UTR binding, this GO :0005515 : protein binding, this GO :0044822 : poly(A) RNA binding, this GO :0045182 : translation regulator activity, this GO :0048027 : mRNA 5'-UTR binding, insulin-like growth factor 2 mRNA binding protein 2 |
| Identity: |
28867 |
| Gene: |
IGF2BP2 |
More about : IGF2BP2 |
| Long gene name: |
insulin like growth factor 2 mRNA binding protein 2 |
| Synonyms gene name: |
insulin-like growth factor 2 mRNA binding protein 2 |
| Synonyms name: |
IGF II mRNA binding protein 2 |
| Locus: |
3q27, 2 |
| Discovery year: |
2006-02-09 |
| GenBank acession: |
BC021290 |
| Entrez gene record: |
10644 |
| Pubmed identfication: |
10190901 9891060 |
| RefSeq identity: |
NM_006548 |
| Classification: |
RNA binding motif containing |
| Havana BLAST/BLAT: |
OTTHUMG00000074025 |