| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
APLP1 |
| Specificity: |
This antibody reacts specifically with APLP1 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Subcellular locations: |
Extracellular |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human APLP1 |
| Gene ID: |
333 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
ALID1, C30, Can regulate neurite outgrowth through binding to components of the extracellular matrix such as heparin and collagen I, Couples to JIP signal transduction through C-terminal binding, May interact with cellular G-protein signaling pathways, The C-terminal gamma-secretase processed fragment, activates transcription activation through APBB1 (Fe65) binding (By similarity), is a potent enhancer of neuronal apoptosis, May play a role in postsynaptic function, The gamma-CTF peptide |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
APLP |
| Also known as: |
APLP1 Polyclonal Antibody |
| Other name: |
Anti-APLP1 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
APLP1 |
| Short name: |
Anti-APLP1 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-amyloid b (A4) precursor-like protein 1 (polyclonal) |
| Alternative technique: |
polyclonals |
| Alternative to gene target: |
APLP, APLP1 and IDBG-45875 and ENSG00000105290 and 333, Aplp1 and IDBG-168935 and ENSMUSG00000006651 and 11803, BT, Plasma membranes, this GO :0005515 and protein binding and molecular function this GO :0005604 and basement membrane and cellular component this GO :0005794 and this GO lgi apparatus and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0006378 and mRNA polyadenylation and biological process this GO :0006417 and regulation of translation and biological process this GO :0006897 and endocytosis and biological process this GO :0006915 and apoptotic process and biological process this GO :0007155 and cell adhesion and biological process this GO :0007193 and adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway and biological process this GO :0007399 and nervous system development and biological process this GO :0008201 and heparin binding and molecular function this GO :0009887 and organ morphogenesis and biological process this GO :0016020 and membrane and cellular component this GO :0016021 and integral component of membrane and cellular component this GO :0030198 and extracellular matrix organization and biological process this GO :0030818 and negative regulation of cAMP biosynthetic process and biological process this GO :0030900 and forebrain development and biological process this GO :0031694 and alpha-2A adrenergic receptor binding and molecular function this GO :0031695 and alpha-2B adrenergic receptor binding and molecular function this GO :0031696 and alpha-2C adrenergic receptor binding and molecular function this GO :0042802 and identical protein binding and molecular function this GO :0046914 and transition metal ion binding and molecular function this GO :0048471 and perinuclear region of cytoplasm and cellular component this GO :0071874 and cellular response to norepinephrine stimulus and biological process, this GO :0005515 : protein binding, this GO :0005515 : protein binding and also this GO :0008201 : heparin binding and also this GO :0031694 : alpha-2A adrenergic receptor binding and also this GO :0031695 : alpha-2B adrenergic receptor binding and also this GO :0031696 : alpha-2C adrenergic receptor binding and also this GO :0042802 : identical protein binding and also this GO :0046914 : transition metal ion binding, this GO :0008201 : heparin binding, this GO :0031694 : alpha-2A adrenergic receptor binding, this GO :0031695 : alpha-2B adrenergic receptor binding, this GO :0031696 : alpha-2C adrenergic receptor binding, this GO :0042802 : identical protein binding, this GO :0046914 : transition metal ion binding, transition metal ion binding, 56047 and IDBG-636032 and ENSBTAG00000001151 and 513154, amyloid beta (A4) precursor-like protein 1 |
| Identity: |
597 |
| Gene: |
APLP1 |
More about : APLP1 |
| Long gene name: |
amyloid beta precursor like protein 1 |
| Synonyms gene name: |
amyloid beta (A4) precursor-like protein 1 |
| Synonyms name: |
amyloid-like protein 1 amyloid precursor-like protein 1 |
| Locus: |
19q13, 12 |
| Discovery year: |
1992-06-18 |
| GenBank acession: |
U48437 |
| Entrez gene record: |
333 |
| Pubmed identfication: |
8432545 |
| RefSeq identity: |
NM_001024807 |
| Havana BLAST/BLAT: |
OTTHUMG00000180692 |