| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
TrkA Tyr791 |
| Specificity: |
This antibody reacts specifically with TrkA (Tyr791) |
| Modification: |
Phosphorylation |
| Modification site: |
Tyr791 |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic phosphopeptide derived from human TrkA around the phosphorylation site of Tyr791 |
| Gene ID: |
4914 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
BDNF and to a lesser extent, By comparison, NGFR p175, NGFR p175 accelerates Trk activation and may recruit downstream dffector molecules to the ligand-bound receptor complex, NT-3, Nerve growth factor (NGF) stimulates tyrosine phosphorylation of Trk gp 140 in neural cell lines and in embryonic dorsal root ganglia, The prototype member of this gene family, The third member of the Trk receptor family, Trk A, Trk C gp140, Trk C incodes a 140 kDa protein, binds to neurotrophic factors with low affinity but is required for efficient signaling, but not NGF, can induce tyrosine phophorylayion of Trk B gp 145, encodes a 140 kDa cell surface receptor , gp140, that is preferentially expressed in brain tissue and primarily functions as a receptor for NT-3, the expression of which is restricted in vivo to neurons of the sensory spinal and cranial gangliaof neurocrest origin, An additional component of the Trk receptor complex, The Trk family of nerve growth factor receptors includes Trk A(also referfed to as Trk A gp140), Trk B and Trk C |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
CIPA, CIPA, DKFZp781I14186, High affinity nerve growth factor receptor, High affinity nerve growth factor receptor precursor, High affinity nerve growth factor receptor precursor, MTC, MTC, NTRK1_HUMAN, Ntrk 1, Ntrk1, Ntrk1, Oncogene TRK, Oncogene TRK, TRK, TRK, TRK 1, TRK1, TRK1 transforming tyrosine kinase protein, TRK1-transforming tyrosine kinase protein, Trk A, Trk-A, TrkA Phospho Tyr791, TrkA Y791, Tropomyosin-related kinase A, Tyrosine Receptor Kinase A, Tyrosine kinase receptor, Tyrosine kinase receptor A, gp140trk, neurotrophic tyrosine kinase receptor type 1, neurotrophic tyrosine kinase receptor type 1, p-TrkATyr791, p140 TrkA, p140-TrkA, TrkA Tyr791 |
| Also known as: |
TrkA (Tyr791) Polyclonal Antibody |
| Other name: |
Anti-TrkA (Tyr791) Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
TrkA (Tyr791) |
| Short name: |
Anti-TrkA (Tyr791) (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-TrkA (Tyr791) (polyclonal) |
| Alternative technique: |
polyclonals |