| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
FbxW2 |
| Specificity: |
This antibody reacts specifically with FbxW2 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human FbxW2 |
| Gene ID: |
26190 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
A large family of mammalian F box proteins has recently been identified and classified into three groups based on the presence of either the WD 40 repeats, F box proteins are one of the four subunits of ubiquitin protein ligases, In fact, SCF ligases bring ubiquitin conjugating enzymes to substrates that are specifically recruited by the different F box proteins, Some F box proteins have been shown to be critical for the ubiquitin mediated degradation of cellular regulatory proteins, The FBXW2 gene product, called SCFs, contains multiple WD 40 repeats, or the presence or absence of other protein protein interacting domains, the F box, the leucine rich repeats, the second identified member of the F box gene family, F box proteins are an expanding family of eukaryotic proteins characterized by an approximately 40 amino acid motif |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
FBW2 Md6 Fwd2 |
| Also known as: |
FbxW2 Polyclonal Antibody |
| Other name: |
Anti-FbxW2 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
FbxW2 |
| Short name: |
Anti-FbxW2 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-FbxW2 (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
13608 |
| Gene: |
FBXW2 |
More about : FBXW2 |
| Long gene name: |
F-box and WD repeat domain containing 2 |
| Synonyms gene name: |
F-box and WD-40 domain protein 2 |
| Locus: |
9q33, 2 |
| Discovery year: |
2000-09-27 |
| GenBank acession: |
AF129531 |
| Entrez gene record: |
26190 |
| Pubmed identfication: |
10531035 10828603 |
| Classification: |
F-box and WD repeat domain containing WD repeat domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000020576 |