| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
Dihydropyrimidinase |
| Specificity: |
This antibody reacts specifically with Dihydropyrimidinase |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human DHP/Dihydropyrimidinase |
| Gene ID: |
1807 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Can catalyzes the ring opening of 5, DHPD is an autosomal recessive disorder characterized by dihydropyrimidinuria and associated with a variable clinical phenotype: epileptic or convulsive attacks, and congenital microvillous atrophy, dysmorphic features and severe developmental delay, the reversible hydrolytic ring opening of dihydropyrimidines, 6-dihydrothymine to N-carbamyl-amino isobutyrate, 6-dihydrouracil to N-carbamyl-alanine and of 5, Catalyzes the second step of the reductive pyrimidine degradation, Involvement in disease:Defects in DPYS are the cause of dihydropyrimidinase deficiency (DHPD), Tissue specificity:Liver and kidney |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
DHPase |
| Also known as: |
Dihydropyrimidinase Polyclonal Antibody |
| Other name: |
Anti-Dihydropyrimidinase Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
Dihydropyrimidinase |
| Short name: |
Anti-Dihydropyrimidinase (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-Dihydropyrimidinase (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
3013 |
| Gene: |
DPYS |
More about : DPYS |
| Long gene name: |
dihydropyrimidinase |
| Locus: |
8q22, 3 |
| Discovery year: |
1997-02-27 |
| GenBank acession: |
D78011 |
| Entrez gene record: |
1807 |
| Pubmed identfication: |
8973361 |
| RefSeq identity: |
NM_001385 |
| Havana BLAST/BLAT: |
OTTHUMG00000164891 |