| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
DCAKD |
| Specificity: |
This antibody reacts specifically with DCAKD |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human DCAKD |
| Gene ID: |
79877 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
DCAKD (deCoA kinase domain containing protein) is a 231 amino acid protein that consists of a deCoA kinase domain and an ATP nucleotide binding motif, DCAKD belongs to the coaE family which suggests that it may play a role in the biosynthesis of CoA, In humans, It contains one DPCK (dephospho CoA kinase) domain, It plays a critical role in the synthesis and oxidation of fatty acids and is vital to the citric acid cycle, Localizing to mitochondria and the cytosol, The biosynthesis pathway of CoA from pantothenic acid (also known as vitamin B5) is essential and universal in prokaryotes and eukaryotes, The phosphopantetheine adenylyltransferase and decoenzyme A kinase activities of COASY are evolutionarily conserved activities, The sequence of these enzymes are highly conserved between different bacterial species, There are two isoforms, the final steps of the biosynthesis pathway are carried out by the bifunctional enzyme COASY, Coenzyme A (CoA) is an essential cofactor used in numerous biochemical pathways, DCAKD belongs to the coaE family |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
FLJ22955 |
| Also known as: |
DCAKD Polyclonal Antibody |
| Other name: |
Anti-DCAKD Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
DCAKD |
| Short name: |
Anti-DCAKD (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-DCAKD (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
26238 |
| Gene: |
DCAKD |
More about : DCAKD |
| Long gene name: |
dephospho-CoA kinase domain containing |
| Locus: |
17q21, 31 |
| Discovery year: |
2005-12-20 |
| GenBank acession: |
BC006546 |
| Entrez gene record: |
79877 |
| RefSeq identity: |
NM_024819 |
| Havana BLAST/BLAT: |
OTTHUMG00000179947 |