| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
ALAD |
| Specificity: |
This antibody reacts specifically with ALAD |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human ALAD |
| Gene ID: |
210 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
AHP is a form of porphyria, AHP is characterized by attacks of gastrointestinal disturbances, Binds two molecules of 5-aminolevulinate per subunit, Most attacks are precipitated by drugs, Porphyrias are inherited defects in the biosynthesis of heme, They are classified as erythropoietic or hepatic, abdominal colic, alcohol, and catalyzes their condensation to form porphobilinogen, and peripheral neuropathy, caloric deprivation, depending on whether the enzyme deficiency occurs in red blood cells or in the liver, each at a distinct site, infections, or endocrine factors, paralysis, resulting in the accumulation and increased excretion of porphyrins or porphyrin precursors, Catalyzes an early step in the biosynthesis of tetrapyrroles, Involvement in disease:Defects in ALAD are the cause of acute hepatic porphyria (AHP) |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
ALADH PBGS |
| Also known as: |
ALAD Polyclonal Antibody |
| Other name: |
Anti-ALAD Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
ALAD |
| Short name: |
Anti-ALAD (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-ALAD (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
395 |
| Gene: |
ALAD |
More about : ALAD |
| Long gene name: |
aminolevulinate dehydratase |
| Synonyms gene name: |
aminolevulinate, dehydratase , delta- |
| Synonyms name: |
porphobilinogen synthase |
| Locus: |
9q32 |
| Discovery year: |
1986-01-01 |
| GenBank acession: |
M13928 |
| Entrez gene record: |
210 |
| Pubmed identfication: |
6839527 6378062 |
| RefSeq identity: |
NM_001003945 |
| Havana BLAST/BLAT: |
OTTHUMG00000020522 |
| Locus Specific Databases: |
ALSOD, the Amyotrophic Lateral Sclerosis Online Genetic Database |