| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
PPP2R1A |
| Specificity: |
This antibody reacts specifically with PPP2R1A |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human PPP2R1A |
| Gene ID: |
5518 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
It consists of a common heteromeric core enzyme, The constant regulatory subunit alpha (PPP2R1A) serves as a scaffolding molecule to coordinate the assembly of the catalytic subunit and a variable regulatory beta subunit, that associates with a variety of regulatory subunits, which is composed of a catalytic subunit and a constant regulatory subunit, Protein phosphatase 2A (PP2A) is the most abundant phosphatase specific for serine and threonine phosphorylation in mammalian cells |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
PR65A PP2A-Aalpha PP2AA |
| Also known as: |
PPP2R1A Polyclonal Antibody |
| Other name: |
Anti-PPP2R1A Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
PPP2R1A |
| Short name: |
Anti-PPP2R1A (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, a (polyclonal), regulatory functionnal sequence A, antibody to-protein phosphatase 2 |
| Alternative technique: |
polyclonals |
| Alternative to gene target: |
DNA-templated and biological process this GO :0006461 and protein complex assembly and biological process this GO :0006470 and protein dephosphorylation and biological process this GO :0006672 and ceramide metabolic process and biological process this GO :0006915 and apoptotic process and biological process this GO :0007059 and chromosome segregation and biological process this GO :0007084 and mitotic nuclear envelope reassembly and biological process this GO :0008380 and RNA splicing and biological process this GO :0008543 and fibroblast growth factor receptor signaling pathway and biological process this GO :0008601 and protein phosphatase type 2A regulator activity and molecular function this GO :0010033 and response to organic substance and biological process this GO :0010467 and gene expression and biological process this GO :0015630 and microtubule cytoskeleton and cellular component this GO :0016020 and membrane and cellular component this GO :0016070 and RNA metabolic process and biological process this GO :0016071 and mRNA metabolic process and biological process this GO :0019932 and second-messenger-mediated signaling and biological process this GO :0030111 and regulation of Wnt signaling pathway and biological process this GO :0030155 and regulation of cell adhesion and biological process this GO :0030308 and negative regulation of cell growth and biological process this GO :0040008 and regulation of growth and biological process this GO :0042518 and negative regulation of tyrosine phosphorylation of Stat3 protein and biological process this GO :0045595 and regulation of cell differentiation and biological process this GO :0046982 and protein heterodimerization activity and molecular function this GO :0070262 and peptidyl-serine dephosphorylation and biological process this GO :2001241 and positive regulation of extrinsic apoptotic signaling pathway in absence of ligand and biological process, PP2A-Aalpha and PP2AAALPHA and PR65A, PPP2R1A and IDBG-641451 and ENSBTAG00000019851 and 535321, PPP2R1A and IDBG-66700 and ENSG00000105568 and 5518, Ppp2r1a and IDBG-141714 and ENSMUSG00000007564 and 51792, alpha, centromeric region and cellular component this GO :0003823 and antigen binding and molecular function this GO :0004722 and protein serine/threonine phosphatase activity and molecular function this GO :0005488 and binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005739 and mitochondrion and cellular component this GO :0005829 and cytosol and cellular component this GO :0006275 and regulation of DNA replication and biological process this GO :0006355 and regulation of transcription, nonsense-mediated decay and biological process this GO :0000188 and inactivation of MAPK activity and biological process this GO :0000278 and mitotic cell cycle and biological process this GO :0000775 and chromosome, nuclei, protein heterodimerization activity, regulatory subunit A, this GO :0000086 and G2/M transition of mitotic cell cycle and biological process this GO :0000159 and protein phosphatase type 2A complex and cellular component this GO :0000184 and nuclear-transcribed mRNA catabolic process, this GO :0003823 : antigen binding, this GO :0003823 : antigen binding and also this GO :0004722 : protein serine/threonine phosphatase activity and also this GO :0005488 : binding and also this GO :0005515 : protein binding and also this GO :0008601 : protein phosphatase type 2A regulator activity and also this GO :0046982 : protein heterodimerization activity, this GO :0004722 : protein serine/threonine phosphatase activity, this GO :0005488 : binding, this GO :0005515 : protein binding, this GO :0008601 : protein phosphatase type 2A regulator activity, this GO :0046982 : protein heterodimerization activity, protein phosphatase 2 |
| Identity: |
9302 |
| Gene: |
PPP2R1A |
More about : PPP2R1A |
| Long gene name: |
protein phosphatase 2 scaffold subunit Aalpha |
| Synonyms gene name: |
alpha isoform , protein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65) |
| Synonyms name: |
65kDa regulatory subunit A protein phosphatase 2A structural subunit A, alpha isoform , alpha isoform protein phosphatase 2, protein phosphatase 2A, regulatory subunit A |
| Locus: |
19q13, 41 |
| Discovery year: |
1993-01-25 |
| Entrez gene record: |
5518 |
| RefSeq identity: |
NM_014225 |
| Classification: |
STRIPAK complex Protein phosphatase 2 scaffold subunits |
| Havana BLAST/BLAT: |
OTTHUMG00000137367 |