| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
SRPK2 |
| Specificity: |
This antibody reacts specifically with SRPK2 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human SRPK2 |
| Gene ID: |
6733 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
It has a role in spliceosome assembly and in mediating the trafficking of splicing factors and appears to mediate HBV core protein phosphorylation which is a prerequisite for pregenomic RNA encapsidation into viral capsids, It phosphorylates RS domain-containing proteins, SRPK2 highly expressed in brain, and kidney, liver, moderately expressed in heart and skeletal muscle and at low levels in lung, such as SFRS1 and SFRS2 on serine residues, SRPK2 belongs to the protein kinase superfamily |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
SFRSK2 |
| Also known as: |
SRPK2 Polyclonal Antibody |
| Other name: |
Anti-SRPK2 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
SRPK2 |
| Short name: |
Anti-SRPK2 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-SRSF protein kinase 2 (polyclonal) |
| Alternative technique: |
polyclonals |
| Alternative to gene target: |
BT, SFRSK2, SRPK2 and IDBG-34933 and ENSG00000135250 and 6733, Srpk2 and IDBG-139589 and ENSMUSG00000062604 and 20817, nuclei, this GO :0000245 and spliceosomal complex assembly and biological process this GO :0000287 and magnesium ion binding and molecular function this GO :0001525 and angiogenesis and biological process this GO :0004672 and protein kinase activity and molecular function this GO :0004674 and protein serine/threonine kinase activity and molecular function this GO :0004713 and protein tyrosine kinase activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005524 and ATP binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005730 and nucleolus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0006468 and protein phosphorylation and biological process this GO :0008152 and metabolic process and biological process this GO :0008284 and positive regulation of cell proliferation and biological process this GO :0008380 and RNA splicing and biological process this GO :0010628 and positive regulation of gene expression and biological process this GO :0016772 and transferase activity, this GO :0000287 : magnesium ion binding, this GO :0000287 : magnesium ion binding and also this GO :0004672 : protein kinase activity and also this GO :0004674 : protein serine/threonine kinase activity and also this GO :0004713 : protein tyrosine kinase activity and also this GO :0005515 : protein binding and also this GO :0005524 : ATP binding and also this GO :0016772 : transferase activity, this GO :0004672 : protein kinase activity, this GO :0004674 : protein serine/threonine kinase activity, this GO :0004713 : protein tyrosine kinase activity, this GO :0005515 : protein binding, this GO :0005524 : ATP binding, this GO :0016772 : transferase activity, this GO :0044822 : poly(A) RNA binding, this GO :0071889 : 14-3-3 protein binding, transferase activity, transferring phosphorus-containing groups, transferring phosphorus-containing groups and also this GO :0044822 : poly(A) RNA binding and also this GO :0071889 : 14-3-3 protein binding, transferring phosphorus-containing groups and molecular function this GO :0030154 and cell differentiation and biological process this GO :0035063 and nuclear speck organization and biological process this GO :0035556 and intracellular signal transduction and biological process this GO :0043525 and positive regulation of neuron apoptotic process and biological process this GO :0044822 and poly(A) RNA binding and molecular function this GO :0045070 and positive regulation of viral genome replication and biological process this GO :0045071 and negative regulation of viral genome replication and biological process this GO :0045087 and innate immune response and biological process this GO :0045787 and positive regulation of cell cycle and biological process this GO :0048024 and regulation of mRNA splicing, via spliceosome and biological process this GO :0071889 and 14-3-3 protein binding and molecular function, 61295 and IDBG-631828 and ENSBTAG00000002175 and 505945, SRSF protein kinase 2 |
| Identity: |
11306 |
| Gene: |
SRPK2 |
More about : SRPK2 |
| Long gene name: |
SRSF protein kinase 2 |
| Synonyms gene name: |
SFRS protein kinase 2 |
| Synonyms name: |
SR protein kinase 2 serine/arginine-rich splicing factor kinase 2 |
| Locus: |
7q22, 3 |
| Discovery year: |
1998-03-02 |
| GenBank acession: |
U88666 |
| Entrez gene record: |
6733 |
| Pubmed identfication: |
8208298 9472028 |
| RefSeq identity: |
NM_182691 |
| Havana BLAST/BLAT: |
OTTHUMG00000157405 |