| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
Robo2 |
| Specificity: |
This antibody reacts specifically with Robo2 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human Robo2 |
| Gene ID: |
6092 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
VUR is a complex, and probably SLIT1, genetically heterogeneous developmental disorder characterized by the retrograde flow of urine from the bladder into the ureter and is associated with reflux nephropathy, including axonal navigation at the ventral midline of the neural tube and projection of axons to different regions during neuronal development, the cause of 15% of end-stage renal disease in children and young adults, which are thought to act as molecular guidance cue in cellular migration, Involvement in disease:Defects in ROBO2 are the cause of vesicoureteral reflux type 2 (VUR2) , Receptor for SLIT2 |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Also known as: |
Robo2 Polyclonal Antibody |
| Other name: |
Anti-Robo2 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
Robo2 |
| Short name: |
Anti-Robo2 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, axon guidance receptor, homolog 2 (Drosophila) (polyclonal), antibody to-roundabout |
| Alternative technique: |
polyclonals |
| Identity: |
44386 |
| Gene: |
ROBO2P1 |
More about : ROBO2P1 |
| Long gene name: |
roundabout guidance receptor 2 pseudogene 1 |
| Synonyms gene name: |
ROBO2 pseudogene 1 |
| Locus: |
7p12, 1 |
| Discovery year: |
2012-09-17 |
| Havana BLAST/BLAT: |
OTTHUMG00000156001 |