| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
UBE2V1 |
| Specificity: |
This antibody reacts specifically with UBE2V1 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human UBE2V1 |
| Gene ID: |
7335 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Mediates transcriptional activation of target genes, Plays a role in the activation of NF-kappa-B mediated by IL1B, Plays a role in the control of progress through the cell cycle and differentiation, Plays a role in the error-free DNA repair pathway and contributes to the survival of cells after DNA damage, TNF, TRAF6 and TRAF2, The UBE2V1-UBE2N heterodimer catalyzes the synthesis of non-canonical poly-ubiquitin chains that are linked through Lys-63, This type of poly-ubiquitination activates IKK and does not seem to involve protein degradation by the proteasome, Has no ubiquitin ligase activity on its own |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
UEV-1 CROC-1 UEV1A CROC1 |
| Also known as: |
UBE2V1 Polyclonal Antibody |
| Other name: |
Anti-UBE2V1 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
UBE2V1 |
| Short name: |
Anti-UBE2V1 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-UBE2V1 (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
12494 |
| Gene: |
UBE2V1 |
More about : UBE2V1 |
| Long gene name: |
ubiquitin conjugating enzyme E2 V1 |
| Synonyms gene: |
UBE2V |
| Synonyms gene name: |
ubiquitin-conjugating enzyme E2 variant 1 |
| Locus: |
20q13, 13 |
| Discovery year: |
1998-03-20 |
| GenBank acession: |
U39360 |
| Entrez gene record: |
7335 |
| Pubmed identfication: |
9418904 9305758 |
| RefSeq identity: |
NM_021988 |
| Classification: |
Ubiquitin conjugating enzymes E2 |
| Havana BLAST/BLAT: |
OTTHUMG00000152626 |