| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
FAM3C |
| Specificity: |
This antibody reacts specifically with FAM3C |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human FAM3C |
| Gene ID: |
10447 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Also, Due to this evidence, Elevated levels of ILEI translation are observed in oncogenic, Ras-transformed mammary epithelial cells and epithelial to mesenchymal transition (Emt) as well as tumor growth and metastasis, a protein involved in tight junctions, and expression of cytoplasmic E-cadherin, it is suspected that ILEI cooperates with oncogenic Ras to cause TGFâ, metastasis and survival in a variety of cancers, overexpression of ILEI results in loss of ZO-1, ubiquitously expressed protein containing an amino-terminal signal peptide, which has been shown to influence loss of polarity and invasiveness, &circ, «, -independent Emt and its overexpression is correlated with the invasion, ILEI is a 227 amino acid |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
GS3876 ILEI |
| Also known as: |
FAM3C Polyclonal Antibody |
| Other name: |
Anti-FAM3C Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
FAM3C |
| Short name: |
Anti-FAM3C (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, member C (polyclonal), antibody to-family including sequence similarity 3 |
| Alternative technique: |
polyclonals |
| Alternative to gene target: |
Extracellular, FAM3C and IDBG-38333 and ENSG00000196937 and 10447, FAM3C and IDBG-634725 and ENSBTAG00000007976 and 615690, Fam3c and IDBG-129573 and ENSMUSG00000029672 and 27999, ILEI, cytokine activity, member C, this GO :0005125 and cytokine activity and molecular function this GO :0005576 and extracellular region and cellular component this GO :0005794 and this GO lgi apparatus and cellular component this GO :0007275 and multicellular organismal development and biological process this GO :0008150 and biological process and biological process this GO :0016023 and cytoplasmic membrane-bounded vesicle and cellular component this GO :0070062 and extracellular vesicular exosome and cellular component, this GO :0005125 : cytokine activity, this GO :0005125 : cytokine activity, family with sequence similarity 3 |
| Identity: |
18664 |
| Gene: |
FAM3C |
More about : FAM3C |
| Long gene name: |
family with sequence similarity 3 member C |
| Synonyms gene name: |
family with sequence similarity 3, member C |
| Synonyms name: |
predicted osteoblast protein interleukin-like EMT inducer interleukin-like epithelial-mesenchymal transition inducer |
| Locus: |
7q31, 31 |
| Discovery year: |
2002-06-18 |
| GenBank acession: |
D87120 |
| Entrez gene record: |
10447 |
| Pubmed identfication: |
12160727 |
| RefSeq identity: |
NM_001040020 |
| Havana BLAST/BLAT: |
OTTHUMG00000156979 |