| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
ZWINT |
| Specificity: |
This antibody reacts specifically with ZWINT |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human ZWINT |
| Gene ID: |
11130 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Inhibition of ZWINT expression results in chromosome missegregation, ZWINT interacts with ZW10 and targets it to the kinetochore at prometaphase, ZWINT is detectable on the kinetochore till late anaphase, cell death upon cytokinesis, spindle checkpoint failure and, ultimately, which is required for kinetochore function and spindle checkpoint activity, ZWINT is a component of the MIS12 complex |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
KNTC2AP SIP30 Zwint1 |
| Also known as: |
ZWINT Polyclonal Antibody |
| Other name: |
Anti-ZWINT Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
ZWINT |
| Short name: |
Anti-ZWINT (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-ZWINT (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
13195 |
| Gene: |
ZWINT |
More about : ZWINT |
| Long gene name: |
ZW10 interacting kinetochore protein |
| Synonyms gene name: |
ZW10 interactor |
| Synonyms name: |
SNAP25 interacting protein of 30 kDa |
| Locus: |
10q21-q22 |
| Discovery year: |
2001-06-22 |
| GenBank acession: |
AF067656 |
| Pubmed identfication: |
10806105 |
| Havana BLAST/BLAT: |
OTTHUMG00000018261 |