| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
CDC123 |
| Specificity: |
This antibody reacts specifically with CDC123 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human CDC123/C10orf7 |
| Gene ID: |
8872 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Cdc123 (Cell division cycle protein 123), Cdc123 functions to destabilize Chfr (checkpoint with forkhead and ring finger domain) proteins which, Cdc123 is thought to be a basal marker for luminal breast cancers, Cdc123 prevents the Chfr proteins from collecting in the cell, Due to its role in cell cycle control, Widely expressed with high expression in thymus, also known as D123, block the G to S phase transition, is a 336 amino acid cytoplasmic protein that is involved in cell cycle control, ovary, small intestine and leukocytes, spleen, testis, thereby allowing the cell to enter the S phase, when accumulated, Required for S phase entry of the cell cycle, The eukaryotic cell division cycle consists of a number of gene-controlled sequences that involve cyclin dependent kinases (Cdks) and cell division control (Cdc) proteins |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
D123 |
| Also known as: |
CDC123 Polyclonal Antibody |
| Other name: |
Anti-CDC123 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
CDC123 |
| Short name: |
Anti-CDC123 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-CDC123 (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
16827 |
| Gene: |
CDC123 |
More about : CDC123 |
| Long gene name: |
cell division cycle 123 |
| Synonyms gene: |
C10orf7 |
| Synonyms gene name: |
cerevisiae) , chromosome 10 open reading frame 7 cell division cycle 123 homolog (S |
| Locus: |
10p14-p13 |
| Discovery year: |
2003-03-10 |
| GenBank acession: |
BC001600 |
| Entrez gene record: |
8872 |
| Pubmed identfication: |
15319434 |
| RefSeq identity: |
NM_006023 |
| Havana BLAST/BLAT: |
OTTHUMG00000017680 |