| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
RACGAP1 |
| Specificity: |
This antibody reacts specifically with RACGAP1 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human RACGAP1 |
| Gene ID: |
29127 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
GAPs may also serve as effector molecules and play a role in signaling downstream of Rho and other Ras-like GTPases, GTPase-activating proteins (GAPs) bind activated forms of Rho GTPases and stimulate GTP hydrolysis, RAC and CDC42, Rho GAPs negatively regulate Rho-mediated signals, There are 3 subtypes of Rho GTPases in the Ras superfamily of small G proteins: RHO, Through this catalytic function, Rho GTPases control a variety of cellular processes |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
MgcRacGAP |
| Also known as: |
RACGAP1 Polyclonal Antibody |
| Other name: |
Anti-RACGAP1 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
RACGAP1 |
| Short name: |
Anti-RACGAP1 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-Rac GTPase activating protein 1 (polyclonal) |
| Alternative technique: |
polyclonals |
| Alternative to gene target: |
RACGAP1 and IDBG-32209 and ENSG00000161800 and 29127, RACGAP1 and IDBG-632426 and ENSBTAG00000012784 and 514618, Racgap1 and IDBG-183510 and ENSMUSG00000023015 and 26934, actomyosin contractile ring assembly and biological process this GO :0001669 and acrosomal vesicle and cellular component this GO :0005096 and GTPase activator activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005547 and phosphatidylinositol-3, initiation of separation and biological process this GO :0007165 and signal transduction and biological process this GO :0007264 and small GTPase mediated signal transduction and biological process this GO :0007283 and spermatogenesis and biological process this GO :0007405 and neuroblast proliferation and biological process this GO :0007596 and blood coagulation and biological process this GO :0008017 and microtubule binding and molecular function this GO :0008272 and sulfate transport and biological process this GO :0009790 and embryo development and biological process this GO :0019886 and antigen processing and presentation of exogenous peptide antigen via MHC class II and biological process this GO :0019901 and protein kinase binding and molecular function this GO :0030496 and midbody and cellular component this GO :0031234 and extrinsic component of cytoplasmic side of plasma membrane and cellular component this GO :0032154 and cleavage furrow and cellular component this GO :0032467 and positive regulation of cytokinesis and biological process this GO :0035556 and intracellular signal transduction and biological process this GO :0038032 and termination of G-protein coupled receptor signaling pathway and biological process this GO :0043014 and alpha-tubulin binding and molecular function this GO :0043015 and gamma-tubulin binding and molecular function this GO :0043547 and positive regulation of GTPase activity and biological process this GO :0046872 and metal ion binding and molecular function this GO :0048487 and beta-tubulin binding and molecular function this GO :0051056 and regulation of small GTPase mediated signal transduction and biological process this GO :0051233 and spindle midzone and cellular component this GO :0051256 and spindle midzone assembly involved in mitosis and biological process this GO :0051988 and regulation of attachment of spindle microtubules to kinetochore and biological process this GO :0070062 and extracellular vesicular exosome and cellular component this GO :0072686 and mitotic spindle and cellular component this GO :0097149 and centralspindlin complex and cellular component, nuclei, phosphatidylinositol-3, this GO :0000281 and mitotic cytokinesis and biological process this GO :0000915 and cytokinesis, this GO :0005096 : GTPase activator activity, this GO :0005096 : GTPase activator activity and also this GO :0005515 : protein binding and also this GO :0005547 : phosphatidylinositol-3, this GO :0005515 : protein binding, this GO :0005547 : phosphatidylinositol-3, this GO :0008017 : microtubule binding, this GO :0019901 : protein kinase binding, this GO :0043014 : alpha-tubulin binding, this GO :0043015 : gamma-tubulin binding, this GO :0046872 : metal ion binding, this GO :0048487 : beta-tubulin binding, 4, 4, 4, 5-trisphosphate binding, 5-trisphosphate binding and also this GO :0008017 : microtubule binding and also this GO :0019901 : protein kinase binding and also this GO :0043014 : alpha-tubulin binding and also this GO :0043015 : gamma-tubulin binding and also this GO :0046872 : metal ion binding and also this GO :0048487 : beta-tubulin binding, 5-trisphosphate binding and molecular function this GO :0005622 and intracellular and cellular component this GO :0005634 and nucleus and cellular component this GO :0005829 and cytosol and cellular component this GO :0005874 and microtubule and cellular component this GO :0007018 and microtubule-based movement and biological process this GO :0007108 and cytokinesis, Rac GTPase activating protein 1 |
| Identity: |
9804 |
| Gene: |
RACGAP1 |
More about : RACGAP1 |
| Long gene name: |
Rac GTPase activating protein 1 |
| Locus: |
12q13, 12 |
| Discovery year: |
1999-09-09 |
| Entrez gene record: |
29127 |
| Pubmed identfication: |
9497316 |
| RefSeq identity: |
NM_013277 |
| Havana BLAST/BLAT: |
OTTHUMG00000169811 |