| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
LAP3 |
| Specificity: |
This antibody reacts specifically with LAP3 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human LAP3 |
| Gene ID: |
51056 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Defects in some of the genes located on chromosome 4 are associated with Huntington's disease, Ellis-van Creveld syndrome, Existing as a homohexamer, LAP3 uses zinc as a cofactor to catalyze the release of an N-terminal proline from a target peptide and is, Multiple isoforms of LAP3 exist due to alternative splicing events, The gene encoding LAP3 maps to human chromosome 4, also known as LAPEP or PEPS, involved in the processing and turnover of intracellular proteins, is a 519 amino acid protein that localizes to the cytoplasm and belongs to the peptidase M17 family, methylmalonic acidemia and polycystic kidney disease, therefore, which houses nearly 6% of the human genome and has the largest gene deserts (regions of the genome with no protein encoding genes) of all of the human chromosomes, LAP3 (leucine aminopeptidase 3) |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
LAPEP LAP |
| Also known as: |
LAP3 Polyclonal Antibody |
| Other name: |
Anti-LAP3 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
LAP3 |
| Short name: |
Anti-LAP3 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-LAP3 (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
18449 |
| Gene: |
LAP3 |
More about : LAP3 |
| Long gene name: |
leucine aminopeptidase 3 |
| Synonyms gene: |
PEPS |
| Synonyms gene name: |
peptidase S |
| Locus: |
4p15, 32 |
| Discovery year: |
2002-04-22 |
| GenBank acession: |
AF061738 |
| Entrez gene record: |
51056 |
| Pubmed identfication: |
6350155 689684 |
| Classification: |
Aminopeptidases |
| Havana BLAST/BLAT: |
OTTHUMG00000048214 |