| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
CIDE A |
| Specificity: |
This antibody reacts specifically with CIDE A |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human CIDE A |
| Gene ID: |
1149 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
CIDE A is a DFF45 inhibitable effector that promotes cell death and DNA fragmentation, CIDE A is expressed in many tissues, CIDE contains a new type of domain termed CIDE N, Cell death signals are transduced by death domain containing adapter molecules and members of the caspase family of proteases, DFF45 related proteins CIDE A and CIDE B (for cell death inducing DFF like effector A and B) were recently identified, DFF45/ICARD has been identified as inhibitor of caspase activated DNase DFF40/CAD, Expression of CIDE A induces DNA fragmentation and activates apoptosis, These death signals finally cause the degradation of chromosomal DNA by activated DNase, which has high homology with the regulatory domains of DFF45/ICAD and DFF40/CAD, which is inhibited by DFF45, Apoptosis is related to many diseases and induced by a family of cell death receptors and their ligands |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
CIDEA, CIDEA_HUMAN, Cell Death Inducing DFFA Like Effector A, alpha subunit like effector A, cell death inducing DNA fragmentation factor, Cell death activator CIDE A |
| Also known as: |
CIDE A Polyclonal Antibody |
| Other name: |
Anti-CIDE A Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
CIDE A |
| Short name: |
Anti-CIDE A (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-CIDE A (polyclonal) |
| Alternative technique: |
polyclonals |