| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
RNF144B |
| Specificity: |
This antibody reacts specifically with RNF144B |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human IBRDC2/RING finger protein 144B |
| Gene ID: |
255488 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
But, However, Induces apoptosis via a p53/TP53-dependent but caspase-independent mechanism, a pro-apoptotic protein, and highest levels detectable in heart, it is not an anti-apoptotic protein per se, its overexpression also produces a decrease of the ubiquitin-dependent stability of BAX, ovary and testis, thereby promoting their degradation, ultimately leading to protection of cell death, with lowest levels in brain and thymus, E3 ubiquitin-protein ligase which accepts ubiquitin from E2 ubiquitin-conjugating enzymes UBE2L3 and UBE2L6 in the form of a thioester and then directly transfers the ubiquitin to targeted substrates such as LCMT2, Tissue specificity: Broadly expressed |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
bA528A10, 3 P53RFP |
| Also known as: |
RNF144B Polyclonal Antibody |
| Other name: |
Anti-RNF144B Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
RNF144B |
| Short name: |
Anti-RNF144B (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-ring finger protein 144B (polyclonal) |
| Alternative technique: |
polyclonals |
| Alternative to gene target: |
BT, Plasma membranes, RNF144B and IDBG-64050 and ENSG00000137393 and 255488, Rnf144b and IDBG-149475 and ENSMUSG00000038068 and 218215, ligase activity, this GO :0000151 and ubiquitin ligase complex and cellular component this GO :0004842 and ubiquitin-protein transferase activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005737 and cytoplasm and cellular component this GO :0006915 and apoptotic process and biological process this GO :0008270 and zinc ion binding and molecular function this GO :0016021 and integral component of membrane and cellular component this GO :0016874 and ligase activity and molecular function this GO :0031966 and mitochondrial membrane and cellular component this GO :0042787 and protein ubiquitination involved in ubiquitin-dependent protein catabolic process and biological process, this GO :0004842 : ubiquitin-protein transferase activity, this GO :0004842 : ubiquitin-protein transferase activity and also this GO :0005515 : protein binding and also this GO :0008270 : zinc ion binding and also this GO :0016874 : ligase activity, this GO :0005515 : protein binding, this GO :0008270 : zinc ion binding, this GO :0016874 : ligase activity, 66635 and IDBG-635837 and ENSBTAG00000009055 and 524166, ring finger protein 144B |
| Identity: |
21578 |
| Gene: |
RNF144B |
More about : RNF144B |
| Long gene name: |
ring finger protein 144B |
| Synonyms gene: |
IBRDC2 |
| Synonyms gene name: |
IBR domain containing 2 |
| Locus: |
6p22, 3 |
| Discovery year: |
2003-06-25 |
| GenBank acession: |
AK096832 |
| Entrez gene record: |
255488 |
| RefSeq identity: |
XM_172581 |
| Classification: |
Ring finger proteins RBR E3 ubiquitin ligases |
| Havana BLAST/BLAT: |
OTTHUMG00000014322 |