| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
Ankyrin erythroid |
| Specificity: |
This antibody reacts specifically with Ankyrin erythroid |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human Ankyrin erythroid |
| Gene ID: |
286 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Ankyrin 1, Complex patterns of alternative splicing in the regulatory domain, Dec 2008], Most ankyrins are typically composed of three structural domains: an amino-terminal domain containing multiple ankyrin repeats, Multiple isoforms of ankyrin with different affinities for various target proteins are expressed in a tissue-specific, Mutations in erythrocytic ankyrin 1 have been associated in approximately half of all patients with hereditary spherocytosis, Truncated muscle-specific isoforms of ankyrin1 resulting from usage of an alternate promoter have also been identified, [provided by RefSeq, a central region with a highly conserved spectrin binding domain, activation, and a carboxy-terminal regulatory domain which is the least conserved and subject to variation, but since has also been found in brain and muscles, contact and the maintenance of specialized membrane domains, developmentally regulated manner, giving rise to different isoforms of ankyrin 1 have been described, proliferation, the prototype of this family, was first discovered in the erythrocytes, Ankyrins are a family of proteins that link the integral membrane proteins to the underlying spectrin-actin cytoskeleton and play key roles in activities such as cell motility |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
ANK-1, ANK1_HUMAN, Ank1, Ankyrin 1, Ankyrin 1, Ankyrin R, Ankyrin-1, Ankyrin-R, Erythrocyte ankyrin, SPH1, SPH2, erythrocytic, ANK |
| Also known as: |
Ankyrin erythroid Polyclonal Antibody |
| Other name: |
Anti-Ankyrin erythroid Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
Ankyrin erythroid |
| Short name: |
Anti-Ankyrin erythroid (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-Ankyrin erythroid (polyclonal) |
| Alternative technique: |
polyclonals |