| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
KLHL20 |
| Specificity: |
This antibody reacts specifically with KLHL20 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human KLHL20 |
| Gene ID: |
27252 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Also acts as a regulator of endothelial migration during angiogenesis by controlling the activation of Rho GTPases, The BCR(KLHL20) E3 ubiquitin ligase complex mediates the ubiquitination of DAPK1, leading to its degradation by the proteasome, thereby acting as a negative regulator of apoptosis, Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex involved in interferon response |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
KLEIP KHLHX |
| Also known as: |
KLHL20 Polyclonal Antibody |
| Other name: |
Anti-KLHL20 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
KLHL20 |
| Short name: |
Anti-KLHL20 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-kelch-like 20 (Drosophila) (polyclonal) |
| Alternative technique: |
polyclonals |
| Alternative to gene target: |
KLHL20 and IDBG-104885 and ENSG00000076321 and 27252, KLHL20 and IDBG-636314 and ENSBTAG00000024485 and 511387, Klhl20 and IDBG-201411 and ENSMUSG00000026705 and 226541, interferon-gamma binding, nuclei, this GO :0003779 and actin binding and molecular function this GO :0004842 and ubiquitin-protein transferase activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005737 and cytoplasm and cellular component this GO :0005794 and this GO lgi apparatus and cellular component this GO :0005802 and trans- this GO lgi network and cellular component this GO :0006895 and this GO lgi to endosome transport and biological process this GO :0007010 and cytoskeleton organization and biological process this GO :0015031 and protein transport and biological process this GO :0015629 and actin cytoskeleton and cellular component this GO :0016567 and protein ubiquitination and biological process this GO :0016605 and PML body and cellular component this GO :0019964 and interferon-gamma binding and molecular function this GO :0030424 and axon and cellular component this GO :0030425 and dendrite and cellular component this GO :0031463 and Cul3-RING ubiquitin ligase complex and cellular component this GO :0035455 and response to interferon-alpha and biological process this GO :0043066 and negative regulation of apoptotic process and biological process this GO :0043161 and proteasome-mediated ubiquitin-dependent protein catabolic process and biological process this GO :0048471 and perinuclear region of cytoplasm and cellular component this GO :1990390 and protein K33-linked ubiquitination and biological process, this GO :0003779 : actin binding, this GO :0003779 : actin binding and also this GO :0004842 : ubiquitin-protein transferase activity and also this GO :0005515 : protein binding and also this GO :0019964 : interferon-gamma binding, this GO :0004842 : ubiquitin-protein transferase activity, this GO :0005515 : protein binding, this GO :0019964 : interferon-gamma binding, kelch-like 20 (Drosophila) |
| Identity: |
25056 |
| Gene: |
KLHL20 |
More about : KLHL20 |
| Long gene name: |
kelch like family member 20 |
| Synonyms gene name: |
kelch-like 20 (Drosophila) |
| Locus: |
1q25, 1 |
| Discovery year: |
2005-02-03 |
| GenBank acession: |
AB026190 |
| Entrez gene record: |
27252 |
| Pubmed identfication: |
14668487 20389280 |
| RefSeq identity: |
NM_014458 |
| Classification: |
BTB domain containing Kelch like |
| Havana BLAST/BLAT: |
OTTHUMG00000040548 |