| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
DLL1 |
| Specificity: |
This antibody reacts specifically with DLL1 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Subcellular locations: |
Extracellular |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human DLL1 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Delta is a membrane protein expressed in heart, Delta promotes the emergence of a population of cells with T cell/NK-cell characteristics, Jagged-2 and Delta, Ligands for Notch include Jagged, Notch proteins have been found to be overexpressed or rearranged in human tumors, While blocking the differentiation of progenitor cells into the B cell lineage, and in adult heart and lung, brain and muscle during gastrulation and early organogenesis, pancreas, The LIN-12/Notch family of transmembrane receptors is believed to play a central role in development by regulating cell fate decisions |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Also known as: |
DLL1 Polyclonal Antibody |
| Other name: |
Anti-DLL1 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
DLL1 |
| Short name: |
Anti-DLL1 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-delta-like 1 (Drosophila) (polyclonal) |
| Alternative technique: |
polyclonals |
| Alternative to gene target: |
DLL1 and IDBG-636101 and ENSBTAG00000031476 and 101908771, DLL1 and IDBG-99280 and ENSG00000198719 and 28514, Dll1 and IDBG-139653 and ENSMUSG00000014773 and 13388, Extracellular, protein binding, this GO :0001709 and cell fate determination and biological process this GO :0001756 and somitogenesis and biological process this GO :0001757 and somite specification and biological process this GO :0001947 and heart looping and biological process this GO :0005112 and Notch binding and molecular function this GO :0005509 and calcium ion binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005576 and extracellular region and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0005887 and integral component of plasma membrane and cellular component this GO :0007154 and cell communication and biological process this GO :0007219 and Notch signaling pathway and biological process this GO :0007220 and Notch receptor processing and biological process this GO :0007267 and cell-cell signaling and biological process this GO :0007275 and multicellular organismal development and biological process this GO :0007368 and determination of left/right symmetry and biological process this GO :0007386 and compartment pattern specification and biological process this GO :0016020 and membrane and cellular component this GO :0016021 and integral component of membrane and cellular component this GO :0030097 and hemopoiesis and biological process this GO :0030154 and cell differentiation and biological process this GO :0030155 and regulation of cell adhesion and biological process this GO :0031410 and cytoplasmic vesicle and cellular component this GO :0032693 and negative regulation of interleukin-10 production and biological process this GO :0045596 and negative regulation of cell differentiation and biological process this GO :0045608 and negative regulation of auditory receptor cell differentiation and biological process this GO :0045638 and negative regulation of myeloid cell differentiation and biological process this GO :0045665 and negative regulation of neuron differentiation and biological process this GO :0045747 and positive regulation of Notch signaling pathway and biological process this GO :0045944 and positive regulation of transcription from RNA polymerase II promoter and biological process this GO :0048839 and inner ear development and biological process this GO :0050767 and regulation of neurogenesis and biological process this GO :0070986 and left/right axis specification and biological process this GO :0072014 and proximal tubule development and biological process this GO :0072070 and loop of Henle development and biological process this GO :0097150 and neuronal stem cell maintenance and biological process, this GO :0005112 : Notch binding, this GO :0005112 : Notch binding and also this GO :0005509 : calcium ion binding and also this GO :0005515 : protein binding, this GO :0005509 : calcium ion binding, this GO :0005515 : protein binding, 788775, delta-like 1 (Drosophila) |
| Identity: |
2908 |
| Gene: |
DLL1 |
More about : DLL1 |
| Long gene name: |
delta like canonical Notch ligand 1 |
| Synonyms gene name: |
delta (Drosophila)-like 1 delta-like 1 (Drosophila) |
| Locus: |
6q27 |
| Discovery year: |
2000-02-11 |
| GenBank acession: |
AF003522 |
| Entrez gene record: |
28514 |
| Havana BLAST/BLAT: |
OTTHUMG00000016078 |