| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
OAS3 |
| Specificity: |
This antibody reacts specifically with OAS3 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human OAS3 |
| Gene ID: |
4940 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Copper, OAS2, OAS3, OAS3 and OASL, The OAS family plays a significant role in the inhibition of cellular protein synthesis, These proteins are induced by interferons and function to convert ATP into 2'- 5'- linked oligomers of adenosine in the presence of double-stranded RNA and magnesium ions, also referred to as p100, and its members are important factors in viral infection resistance, apoptosis and growth, contains three adjacent OAS1-like domains and maps to the human chromosome 12q24, iron and zinc ions strongly inhibit the OAS enzymatic activity, while manganese ions can replace magnesium ions as an activator, 2, The 2'- 5'- oligoadenylate synthetase (OAS) family is comprised of four members: OAS1 |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Also known as: |
OAS3 Polyclonal Antibody |
| Other name: |
Anti-OAS3 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
OAS3 |
| Short name: |
Anti-OAS3 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-OAS3 (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
8088 |
| Gene: |
OAS3 |
More about : OAS3 |
| Long gene name: |
2', -5', -oligoadenylate synthetase 3 |
| Synonyms gene name: |
100kDa , 2', -5', -5', -oligoadenylate synthetase 3, -oligoadenylate synthetase 3 (100 kD) 2' |
| Locus: |
12q24, 13 |
| Discovery year: |
1998-06-10 |
| GenBank acession: |
AF063613 |
| Entrez gene record: |
4940 |
| Pubmed identfication: |
9790745 |
| Havana BLAST/BLAT: |
OTTHUMG00000169795 |